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Pore Formation during Laser Welding in Different Spatial Positions
摘要： The process of formation of pores, cavities and similar defects in welded joints of stainless steels and aluminum alloys, affecting their quality, directly depends on spatial weld position in laser welding. Reducing the angle of inclination from 90° to 0° during downhill and uphill welding of AISI 321 stainless steel in the pulse mode of laser generation leads to an increase in both the number of pores and their size. At the same time, defects in the form of pores are not observed in the continuous mode of laser generation. In laser welding of butt joints of AISI 321 steel, the flat and vertical weld positions are the most promising, as they provide the highest level of quality. In order to provide a stable formation of a high-quality butt joint of aluminum AMg6M alloy and to prevent the failure of laser equipment, the welding process should be carried out in a vertical uphill weld position.
关键词： different spatial position,aluminium alloy,stainless steel,quality,defects,porosity,laser welding
更新于2025-09-23 15:21:01
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Selective Laser Sintering 3D Printing a?? An Overview of the Technology and Pharmaceutical Applications
摘要： Food and Drug Administration (FDA) has approved a drug product (Spritam?) and many medical devices manufactured by 3-dimensional printing (3DP) processes for human use. There is immense potential to print personalized medicines using 3DP. Many 3DP methods have been reported in the literature for pharmaceutical applications. However, selective laser sintering (SLS) printing has remained least explored for pharmaceutical applications. There are many advantages and challenges in adopting a SLS method for fabrication of personalized medicines. Solvent free nature, availability of FDA approved thermoplastic polymer/excipients (currently used in hot melt-extrusion process), minimal/no post-processing step, etc. are some of the advantages of the SLS printing process. Major challenges of the technology are requirement of at least one thermoplastic component in the formulation and thermal stability of drug and excipients. This review provides an overview of the SLS printing method, excipient requirements, process monitoring, quality defects, regulatory aspects and potential pharmaceutical applications.
关键词： in-process monitoring,selective laser sintering,personalized medication,3D printing,quality defects,pharmaceuticals
更新于2025-09-23 15:21:01