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Factors influencing the choice of low-vision devices for visual rehabilitation in Stargardt disease
摘要： Background: Stargardt disease is the most common cause of juvenile macular degeneration leading to early central visual loss. Dispensing of correct low-vision devices based on the residual visual function and specific visual requirements of a patient can result in a positive outcome. It is important to know the factors involved in the selection of these devices. This study was undertaken to assess these factors. Methods: Patients with Stargardt disease referred to a low-vision clinic underwent evaluation of visual status, disease stage, visual requirements and lifestyle. They were evaluated for suitability for successful use of various low-vision devices. Their education level and occupation were noted. They were counselled regarding the proper use of the devices and lifestyle modifications. For patients with extensive use of computers, modifications related to contrast, font size and audio software were explained. Results: Among the 97 patients in the study (age range 7–66 years, mean 23.7 ± 13.1), there were 49 (50.5 per cent) students, 36 (37.1 per cent) employed, eight (8.2 per cent) unemployed, and four (4.2 per cent) homemakers. Except for seven patients (7.2 per cent), all were literate, with education ranging from primary school to college graduation. The presenting visual acuity for distance was 0.10–1.47 (0.79 ± 0.28), and for near was N4–N40 (N9.95 ± 6.65). This acuity showed positive correlation with age (p < 0.0001, R2 = 0.16) and with magnification required (p < 0.0001, R2 = 0.26). Patients above 40 years preferred higher adds and half-eye glasses, whereas younger patients preferred dome magnifiers. The occupation also influenced the choice. Disease stage was seen to affect the choice with advanced stages requiring higher magnifiers (p = 0.03, R2 = 0.11). Duration of disease and the magnification of low-vision devices showed a positive correlation (p = 0.03, R2 = 0.049). Conclusions: Age, presenting visual acuity, disease stage, duration, education and occupation influenced the choice of low-vision devices in patients with Stargardt disease. However, they appear to be interdependent and a larger, controlled study is required to provide information on the individual effect.
关键词： occupation,visual rehabilitation,heredomacular degeneration,Stargardt disease,low vision rehabilitation,low vision devices
更新于2025-09-23 15:23:52
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Improvement in reading performance through training with simulated thalamic visual prostheses
摘要： Simulations of artificial vision are used to provide the researcher an opportunity to explore different aspects of visual prosthesis device design by observing subject performance on various tasks viewed through the simulation. Such studies typically use normal, sighted subjects to measure performance at a given point in time. Relatively few studies examine performance changes longitudinally to quantitatively assess the benefits from a training plan that would be akin to post-implantation rehabilitation. Here, we had six normal, sighted subjects use a standard reading task with daily practice over eight weeks to understand the effects of an intensive training schedule on adaptation to artificial sight. Subjects read 40 MNREAD-style sentences per session, with a new set each session, that were presented at five font sizes (logMAR 1.0–1.4) and through three center-weighted phosphene patterns (2,000, 1,000, 500 phosphenes). We found that subjects improved their reading accuracy across sessions, and that the training lead to an increase of reading speed that was equivalent to a doubling of available phosphenes. Most importantly, the hardest condition, while initially illegible, supported functional reading after training. Consistent with experience-driven neuroplastic changes, gaps in the training schedule lead to transient decreases in reading speed, but, surprisingly, not reading accuracy. Our findings contribute to our larger project of developing a thalamic visual prosthesis and to post-implant rehabilitation strategies.
关键词： training,simulation,rehabilitation,artificial vision,reading performance,visual prosthesis,phosphene patterns
更新于2025-09-23 15:23:52
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Training of Hand Rehabilitation Using Low Cost Exoskeleton and Vision-Based Game Interface
摘要： Motivating game-based training have the potential to improve therapy for people with neurological impairments. In recent years, the serious games have become extremely useful tools in rehabilitation field. They aim to stimulate the mobility of the body through an immersive experience that puts the user in interactive virtual environment. This paper is concerned about developing a customized augmented reality system for stroke rehabilitation. This will be done through integrating an interactive serious game interface with a hand exoskeleton device. This game-based rehabilitation system allows users to carry out physical rehabilitation therapies using a natural user interface based on Kinect’s skeletal tracking features and the electromyography (EMG) sensor. During game playing, the interactive user interface provides useful real-time feedback information such as the time required to grasp a desired dynamic virtual object, and the assigned score and thus the ability of the proposed system to provide a compensatory action regarding the dynamic behavior of the virtual target. The main goal of the developed virtual environment is to create positive influences on the rehabilitation process. Patient movement information and signals obtained from the developed exoskeleton device are used together to monitor the rehabilitation progress. The developed exoskeleton hand is a 3D printed low cost device suitable for grasping tasks that can be used even for domestic stroke patients. The developed exoskeleton device is not only a mechanical system able to perform the rehabilitation act but also it presents an effective tracking and traceability software solution. The EMG signals measured during hand motion are used to detect the intention of hand opening or closing which in turn will actuate the mechanical structure to accomplish the desired task. Parameters and results of patients’ exercises are stored and analyzed when needed to evaluate patients’ progress. The developed system is tested experimentally and it is able to restore the functions of the upper limb and mainly give patients more motivation to undergo the rehabilitation exercises.
关键词： Robotic exoskeleton,EMG control,Kinect sensor,3D printing,Stroke rehabilitation
更新于2025-09-23 15:22:29
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Stereo vision system for human motion analysis in a rehabilitation context
摘要： The present demographic trends point to an increase in aged population and chronic diseases which symptoms can be alleviated through rehabilitation. The applicability of passive 3D reconstruction for motion tracking in a rehabilitation context was explored using a stereo camera. The camera was used to acquire depth and color information from which the 3D position of prede?ned joints was recovered based on: kinematic relationships, anthropometrically feasible lengths and temporal consistency. Finally, a set of quantitative measures were extracted to evaluate the performed rehabilitation exercises. Validation study using data provided by a marker based as ground-truth revealed that our proposal achieved errors within the range of state-of-the-art active markerless systems and visual evaluations done by physical therapists. The obtained results are promising and demonstrate that the developed methodology allows the analysis of human motion for a rehabilitation purpose.
关键词： stereo vision,biomedical engineering,Rehabilitation,human motion tracking
更新于2025-09-23 15:21:21
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Artificial pupil versus contralateral balanced contact lens fit for presbyopia correction
摘要： Purpose: To assess and compare the effects of contact lens-based artificial pupil design and contralateral balanced multifocal contact lens combination (CBMCLC) on visual performance. Methods: This randomized crossover study conducted at the University of Valencia, Spain included 38 presbyopic patients using an artificial pupil contact lens in the nondominant eye and a CBMCLC. After a month of lens wear, the binocular distance visual acuity (BDVA), binocular near visual acuity (BNVA), defocus curve, binocular distance, and near contrast sensitivity and near stereoacuity (NSA) were measured under photopic conditions (85 cd/m2). Moreover, BDVA and binocular distance contrast sensitivity were examined under mesopic conditions (5 cd/m2). Results: Visual acuity at an intermediate distance and near vision was better with the CBMCLC than with the artificial pupil (p<0.05). Statistically significant differences were found in contrast sensitivity between the two types of correction for distance (under mesopic conditions) and for near vision, with the CBMCLC exhibiting better results in both cases (p<0.05). The mean NSA values obtained for the artificial pupil contact lens were significantly worse than those for the CBMCLC (p=0.001). Conclusion: The CBMCLC provided greater visual performance in terms of intermediate and near vision compared with the artificial pupil contact lens.
关键词： Prosthesis fitting,Pupil,Presbyopia/rehabilitation,Dominance, ocular,Contact lenses
更新于2025-09-23 15:21:01
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[IEEE 2019 Photonics & Electromagnetics Research Symposium - Fall (PIERS - Fall) - Xiamen, China (2019.12.17-2019.12.20)] 2019 Photonics & Electromagnetics Research Symposium - Fall (PIERS - Fall) - Flexible Spoof Plasmonic Microfluidic Sensor for Detecting Liquid Solutions
摘要： Evaluating patient progress and making discharge decisions regarding inpatient medical rehabilitation rely upon the standard clinical assessments administered by trained clinicians. Wearable inertial sensors can offer more objective measures of patient movement and progress. We undertook a study to investigate the contribution of wearable sensor data to predict discharge functional independence measure (FIM) scores for 20 patients at an inpatient rehabilitation facility. The FIM utilizes a seven-point ordinal scale to measure patient independence while performing several activities of daily living, such as walking, grooming, and bathing. Wearable inertial sensor data were collected from ecological ambulatory tasks at two time points mid-stay during inpatient rehabilitation. Machine learning algorithms were trained with sensor-derived features and clinical information obtained from medical records at admission to the inpatient facility. While models trained only with clinical features predicted discharge scores well, we were able to achieve an even higher level of prediction accuracy when also including the wearable sensor-derived features. Correlations as high as 0.97 for leave-one-out cross validation predicting discharge FIM motor scores are reported.
关键词： prediction,machine learning,Rehabilitation monitoring,signal processing,wearable sensors
更新于2025-09-23 15:19:57
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Photobiomodulation Therapy is Able to Modulate PGE <sub/>2</sub> Levels in Patients With Chronic Nona??Specific Low Back Pain: A Randomized Placeboa??Controlled Trial
摘要： Background and Objectives: Non‐specific low back pain (LBP) is responsible for triggering increased biomarkers levels. In this way, photobiomodulation therapy (PBMT) may be an interesting alternative to treat these patients. One of the possible biological mechanisms of PBMT involved to decrease pain intensity in patients with musculoskeletal disorders is modulation of inflammatory mediators’ levels. The aim of this study was to evaluate the effects of PBMT compared with placebo on inflammatory mediators’ levels and pain intensity in patients with chronic non‐specific LBP. Study Design/Materials and Methods: A prospectively registered, randomized triple‐blinded (volunteers, therapists, and assessors), placebo‐controlled trial was performed. Eighteen patients with chronic non‐specific LBP were recruited and treated with a single session of active PBMT or placebo PBMT. The primary outcome of the study was serum prostaglandin E2 levels and the secondary outcomes were tumor necrosis factor‐α, interleukin‐6 levels, and pain intensity. All outcomes were measured before and after 15 minutes of treatment session. Results: PBMT was able to decrease prostaglandin E2 levels at post‐treatment compared with placebo, with a mean difference of ?1470 pg/ml, 95% confidence interval ?2906 to ?33.67 in patients with LBP. There was no difference between groups in the other measured outcomes. Patients did not report any adverse events. Conclusion: Our results suggest that PBMT was able to modulate prostaglandin E2 levels, indicating that this may be one of the mechanisms involved in the analgesic effects of PBMT in patients with LBP.
关键词： low‐level laser therapy,inflammatory mediators,low back pain,physical therapy,rehabilitation,musculoskeletal disorders
更新于2025-09-23 15:19:57
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[IEEE 2019 IEEE 46th Photovoltaic Specialists Conference (PVSC) - Chicago, IL, USA (2019.6.16-2019.6.21)] 2019 IEEE 46th Photovoltaic Specialists Conference (PVSC) - Photoinduced phase segregation and degradation of perovskites revealed by x-ray photoelectron spectroscopy
摘要： A study was conducted to investigate the criterion validity of measures of upper extremity (UE) motor function derived during practice of virtual activities of daily living (ADLs). Fourteen hemiparetic stroke patients employed a Virtual Occupational Therapy Assistant (VOTA), consisting of a high-fidelity virtual world and a Kinect? sensor, in four sessions of approximately one hour in duration. An unscented Kalman Filter-based human motion tracking algorithm estimated UE joint kinematics in real-time during performance of virtual ADL activities, enabling both animation of the user's avatar and automated generation of metrics related to speed and smoothness of motion. These metrics, aggregated over discrete sub-task elements during performance of virtual ADLs, were compared to scores from an established assessment of UE motor performance, the Wolf Motor Function Test (WMFT). Spearman's rank correlation analysis indicates a moderate correlation between VOTA-derived metrics and the time-based WMFT assessments, supporting the criterion validity of VOTA measures as a means of tracking patient progress during an UE rehabilitation program that includes practice of virtual ADLs.
关键词： Human computer interaction,occupational therapy,patient rehabilitation,human motion tracking,virtual reality,human motor performance
更新于2025-09-23 15:19:57
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[IEEE 2018 16th Biennial Baltic Electronics Conference (BEC) - Tallinn, Estonia (2018.10.8-2018.10.10)] 2018 16th Biennial Baltic Electronics Conference (BEC) - Photoplethysmography-based estimation of heart rate recovery using a wrist-worn device
摘要： Estimation of pulse rate from photoplethysmogram (PPG) signals has led to a breakthrough in a smart wristband technology. This study introduces a method for estimating heart rate recovery (HRR) using a custom-made wrist-worn device, capable of acquiring instantaneous pulse rate, as well as a consumer smart wristband, which provides pulse rate at intervals of 5 s or longer. The feasibility to estimate HRR parameters using the PPG-based devices was assessed by comparing to the synchronously acquired reference electrocardiogram. Three HRR parameters were studied on pulse rate data, obtained from 22 healthy participants, instructed to perform standardized stair climbing test. Study findings show that HRR parameters, estimated using the wrist-worn device, are associated with twice lower absolute error compared to the consumer smart wristband, emphasizing the importance of an instantaneous pulse rate to ensure a sufficiently accurate parameter estimation.
关键词： rehabilitation,free-living activities,smart wristband,physical activity,stair climbing
更新于2025-09-19 17:15:36
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[IEEE 2018 IEEE SENSORS - New Delhi, India (2018.10.28-2018.10.31)] 2018 IEEE SENSORS - A Fiber Bragg Grating Strain Sensor-Based Glove to Accurately Measure the Bend Angle of the Finger Flexed at the Proximal Interphalangeal Joints
摘要： Accurate measurement of finger joint angles is very important in the fields such as rehabilitation, bionics, etc. In this paper, we present a fiber Bragg grating (FBG) sensor-based flexure sensing glove to measure the finger joint angles with high accuracy. We evaluate its accuracy and repeatability on four human subjects by measuring their proximal interphalangeal (PIP) joint angles of the index, middle and the ring fingers. Our glove showed excellent agreement (R-Squared: 0.9985) with the inertial measurement unit (IMU) sensor readings. The glove outperforms several existing sensors exhibiting a maximum error (1.42 degrees), mean error (0.45 degrees) and maximum standard deviation (0.56 degrees). In the future, the study will be extended to all the joints.
关键词： rehabilitation,flexure sensor,instrumented glove,fiber Bragg grating
更新于2025-09-19 17:15:36