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A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
摘要： Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and biocompatibility, but also their by-products induced infection after therapy or long-time treatment in vivo. Thus, the development of novel implant materials is quite urgent. Red phosphorus has great biocompatibility and exhibits efficient photothermal ability. Herein, a red phosphorus/IR780/arginine-glycine-asparticacid-cysteine (RGDC) coating on titanium bone-implant was prepared. The temperature sensitivity of Staphylococcus aureus biofilm is enhanced in the presence of ROS produced by IR780 with 808 nm light irradiation. With keeping the cells and tissues normal, a high antibacterial performance can be realized by near-infrared (808 nm) irradiated within 10 min at 50 °C. Besides the high effective antibacterial efficacy provided by photothermal therapy (PTT) and photodynamic therapy (PDT), the RGDC decorated surface can also possess an excellent performance in osteogenesis in vivo.
关键词： Implants,Biofilm,Red phosphorus,Antibacterial,Osteogenesis,Near-infrared
更新于2025-09-04 15:30:14
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Cu-Doped TiO2: Visible Light Assisted Photocatalytic Antimicrobial Activity
摘要： Surface contamination by microbes is a major public health concern. A damp environment is one of potential sources for microbe proliferation. Smart photocatalytic coatings on building surfaces using semiconductors like titania (TiO2) can effectively curb this growing threat. Metal-doped titania in anatase phase has been proven as a promising candidate for energy and environmental applications. In this present work, the antimicrobial efficacy of copper (Cu)-doped TiO2 (Cu-TiO2) was evaluated against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) under visible light irradiation. Doping of a minute fraction of Cu (0.5 mol %) in TiO2 was carried out via sol-gel technique. Cu-TiO2 further calcined at various temperatures (in the range of 500–700 ?C) to evaluate the thermal stability of TiO2 anatase phase. The physico-chemical properties of the samples were characterized through X-ray diffraction (XRD), Raman spectroscopy, X-ray photo-electron spectroscopy (XPS) and UV–visible spectroscopy techniques. XRD results revealed that the anatase phase of TiO2 was maintained well, up to 650 ?C, by the Cu dopant. UV–vis results suggested that the visible light absorption property of Cu-TiO2 was enhanced and the band gap is reduced to 2.8 eV. Density functional theory (DFT) studies emphasize the introduction of Cu+ and Cu2+ ions by replacing Ti4+ ions in the TiO2 lattice, creating oxygen vacancies. These further promoted the photocatalytic efficiency. A significantly high bacterial inactivation (99.9999%) was attained in 30 min of visible light irradiation by Cu-TiO2.
关键词： Staphylococcus aureus,phase transition,antibacterial coatings,photocatalysis,doping,Cu-doped TiO2,Escherichia coli
更新于2025-09-04 15:30:14
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Studies on growth and characterization of (E)-N′-[4-(dimethylamino) benzylidene]-4-hydroxybenzohydrazide hemihydrate: a nonlinear optical material
摘要： Hydrazone compound (E)-N′-[4-(dimethylamino) benzylidene]-4-hydroxybenzohydrazide hemihydrate (DMABHBH) was synthesized and single crystals of DMABHBH were grown by solvent evaporation method at room temperature. Molecular structure of DMABHBH compound was confirmed by 1H and 13C nuclear magnetic resonance techniques. The presence of functional groups was confirmed by Fourier transform infrared and FT Raman spectral analyses. The X-ray crystal structure was elucidated at 173 K by single crystal X-ray diffraction and the results were compared with the corresponding values obtained at 298 K. The compound crystallizes in the chiral monoclinic space group P21. Mechanical stability of the grown crystals was estimated from the Vicker’s microhardness test. Powder second harmonic generation efficiency of DMABHBH is about 1.1 times that of potassium dihydrogen phosphate. DMABHBH is found to show optical limiting behavior at high input light intensities, the third order nonlinear optical absorption coefficient measured using open aperture Z-scan studies, is 0.95 × 10?11 m/W. Anti-bacterial activity was studied using the well and disc diffusion methods.
关键词： X-ray diffraction,Mechanical properties,Nonlinear optical material,Thermal analysis,Antibacterial activity,Hydrazone,Crystal growth
更新于2025-09-04 15:30:14
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Visible active reduced graphene oxide loaded Titania for photodecomposition of ciprofloxacin and its antibacterial activity
摘要： The reduced Graphene Oxide based titanium dioxide (rGO-TiO2) nanocomposite was synthesized by a simple hydrothermal preparation and characterized by X-ray Diffraction Analysis (XRD), UV–Vis absorption spectroscopy (UV), Fourier Transform Infrared spectroscopy (FT-IR), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). The XRD pattern of rGO-TiO2 indicates the presence of anatase TiO2 and average crystalline size of particles is 32 nm. The optical band gaps of TiO2, GO and rGO-TiO2 nanocomposite are 3.24 eV, 4.3 eV and 2.7 eV respectively. Comparison of efficiencies of three catalysts shows that ciprofloxacin degrades at a faster rate under visible light irradiation in the presence of rGO-TiO2 at 60 min than in presence of pure TiO2 commercial TiO2-P25. Higher photocatalytic decomposition efficiency of rGO-TiO2 is explained by its reduced electron-hole recombination and visible light activity. The kinetics of photodecomposition reaction was analyzed. Antibacterial activity analysis of rGO-TiO2 nanoparticles reveals that it is more active against S. aureus than E.coli.
关键词： Titania,Antibacterial activity,Photocatalytic decomposition,Ciprofloxacin,Reduced graphene oxide
更新于2025-09-04 15:30:14
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Antibacterial and photocatalytic activity of hydrothermally synthesized SnO2 doped GO and CNT under visible light irradiation
摘要： Bacterial and dye pollution are major problems with wastewater treatment. An increasing number of photocatalysts are being used in industry to kill bacterial and reduce pollution. In the present study, highly stable SnO2-doped nanocomposites have been prepared successively by a hydrothermal method. The synthesized nanocomposite was characterized using a range of techniques, such as X-ray diffraction, field emission scanning electron microscopy with energy dispersive X-ray spectroscopy and electron probe micro analysis, ultraviolet–visible spectroscopy, Fourier transform infrared spectroscopy, and high resolution transmission electron microscopy (HR-TEM). The nanocomposites showed significant dose-dependent bactericidal activity in the disc diffusion assay and cell viability test. The S-GO-SnO2 200 μg/mL produced a cell viability of 184.3 ± 11.71 and 172.3 ± 3.05 × 106 CFU/mL for E. coli and P. graminis, respectively. The S-GO-SnO2 showed significant photocatalytic degradation against MB in 120 min. The photocatalyst S-GO-SnO2 showed 159 and 161 × 106 CFU/mL at 150 min in E. coli and P. graminis, respectively. The cells treated with photocatalytic SnO2-doped nanocomposites showed 50% cell death. HR-TEM revealed 50% cell growth inhibition by bacterial damage. This photocatalytic SnO2-doped nanocomposite is a good candidate for treating industrial wastewater treatment contaminated with dyes and bacteria.
关键词： Antibacterial activity,Photocatalytic activity,Hydrothermal syntheses,Visible light irradiation,SGO-SnO2,SCNT-SnO2
更新于2025-09-04 15:30:14