- 标题
- 摘要
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Can standard deviation of overnight pulse oximetry be used to screen childhood obstructive sleep apnea
摘要： Objectives: Pulse oximetry (PO) has been frequently used as an alternative test to polysomnography (PSG) in children. We conducted this study to determine which statistical parameters obtained from overnight PO monitoring would be most suitable and to evaluate its diagnostic performance. Methods: We prospectively recruited children with snoring referred for PSG. Subjects were monitored with PO while performing PSG. Eight statistical parameters of SpO2 data were analyzed to identify which had the best diagnostic performance as assessed by the area under the receiver-operating characteristic curve (AUC). To validate this parameter (which was found to be the standard deviation, SD) in a larger population, we retrospectively extracted raw data of SpO2 from our previous PSG records, calculated the SD of each patient, and assessed its AUC. Results: A total of 166 children were recruited in the first phase. SD of SpO2 was found to have the largest AUC. In the second phase, raw data of 457 patients were extracted. SD of SpO2 correlated well with the apnea/hypopnea index (AHI) (r=0.6, P<0.001). For diagnosis of moderate to severe obstructive sleep apnea (OSA) (AHI ≥5 events/h), AUC was 0.74. SD of SpO2 ≥1.06 representing mean + 2SD of normal to mild OSA (AHI <5) provided 97% specificity and 92% positive predictive value. The positive likelihood ratio was 11. Conclusion: Calculating the SD of SpO2, which quantifies the amount of dispersion of SpO2 values, is a useful initial investigation in childhood OSA. An SD ≥1.06 can predict moderate to severe OSA with confidence. This parameter is simple, practical, and readily accessible.
关键词： Adenotonsillectomy,Screening test,Children,Obstructive sleep apnea,Polysomnography
更新于2025-09-23 15:22:29
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Tests of a New Drowsiness Characterization and Monitoring System Based on Ocular Parameters
摘要： Drowsiness is the intermediate state between wakefulness and sleep. It is characterized by impairments of performance, which can be very dangerous in many activities and can lead to catastrophic accidents in transportation or in industry. There is thus an obvious need for systems that are able to continuously, objectively, and automatically estimate the level of drowsiness of a person busy at a task. We have developed such a system, which is based on the physiological state of a person, and, more specifically, on the values of ocular parameters extracted from images of the eye (photooculography), and which produces a numerical level of drowsiness. In order to test our system, we compared the level of drowsiness determined by our system to two references: (1) the level of drowsiness obtained by analyzing polysomnographic signals; and (2) the performance of individuals in the accomplishment of a task. We carried out an experiment in which 24 participants were asked to perform several Psychomotor Vigilance Tests in different sleep conditions. The results show that the output of our system is well correlated with both references. We determined also the best drowsiness level threshold in order to warn individuals before they reach dangerous situations. Our system thus has significant potential for reliably quantifying the level of drowsiness of individuals accomplishing a task and, ultimately, for preventing drowsiness-related accidents.
关键词： drowsy driving,drowsiness,photooculography,psychomotor vigilance test,monitoring,polysomnography
更新于2025-09-23 15:22:29
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[IEEE 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - Honolulu, HI, USA (2018.7.18-2018.7.21)] 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) - An Ultra-miniaturized Near Infrared Spectroscopy System to Assess Sleep Apnea in Children with Down Syndrome
摘要： Down syndrome is one of the health disorders that interferes with regular and healthy sleep. Most children with Down syndrome are referred to a sleep clinic for the assessment of the severity of their apnea. Regular polysomnography based assessment of apnea has been challenging with this sensitive patient population. We present our efforts towards developing a flexible adhesive bandage sized near infrared spectroscopy system (pediBand) for home-assessment of apnea in children with Down syndrome. Combined with inertial measurement units, pediBand record heart rate, heart rate variability, respiratory rate, arterial oxygen saturation and cerebral oxygen saturation. These are the essential parameters to assess sleep apnea and could also potentially be used in the assessment of sleep performance in general. A modified version of pediBand system was evaluated on adult patients and successfully demonstrated the changes in hemodynamic system triggered by sleep apnea.
关键词： polysomnography,sleep,inertial measurement units,Down syndrome,Near infrared spectroscopy
更新于2025-09-11 14:15:04