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Comparison of Upright Digital Breast Tomosynthesis–guided versus Prone Stereotactic Vacuum-assisted Breast Biopsy
摘要： To compare the performance of upright digital breast tomosynthesis (DBT)–guided vacuum-assisted breast biopsy (VABB) with that of prone stereotactic (PS) VABB. This retrospective review involved consecutive patients who underwent PS VABB from August 2014 to December 2015 and upright DBT-guided VABB from February 2016 to June 2017. Tissue sampling methods were the same for PS and DBT-guided biopsies. Wilcoxon and Pearson x2 tests were used to compare the groups. During the study period, 439 PS VABBs in 408 patients (mean age, 56.5 years; age range, 32–84 years) and 706 DBT-guided VABBs in 682 patients (mean age, 57.9 years; age range, 23–90 years) were recommended. Technical success was achieved for more lesions with DBT-guided VABB versus PS VABB (99.3% [695 of 700] vs 95.1% [410 of 431], respectively; P , .001). Mean procedure time was shorter with DBT-guided VABB versus PS VABB (12 vs 27 minutes, respectively; P , .001), and fewer exposures were acquired with DBT-guided VABB versus PS VABB (three vs 12, respectively; P , .001). A higher percentage of lesions for which DBT-guided VABB was performed were noncalcified lesions (eg, architectural distortion, asymmetry, and mass) than for PS VABB (29.2% [203 of 695] vs 3.4% [14 of 410], respectively; P , .001). There were no differences in the distribution of histologic results (P = .42). No major complications were observed in either group. Upright digital breast tomosynthesis–guided vacuum-assisted breast biopsy has a higher rate of technical success than does prone stereotactic vacuum-assisted biopsy and can be performed in less than half the time and with one-fourth of the exposures. In addition, more architectural distortions and asymmetries are amenable to biopsy with digital breast tomosynthesis–guided vacuum-assisted breast biopsy.
关键词： upright biopsy,prone stereotactic,digital breast tomosynthesis,breast cancer,vacuum-assisted breast biopsy
更新于2025-09-09 09:28:46
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Comparison of Digital Breast Tomosynthesis (DBT) and Digital Mammography (DM) for Detection of Breast Cancer in Women in Kuwait
摘要： Objective: To investigate the sensitivity and specificity of digital mammography (DM) and digital breast tomosynthesis (DBT) for the detection of breast cancer in comparison to histopathology findings. Subjects and Methods: We included 65 breast lesions in 58 women, each detected by two diagnostic mammography techniques: DM and DBT using Senographe Essential machine (GE Healthcare, Buc, France), and subsequently confirmed by histopathology. The Breast Imaging-Reporting and Data System (BI-RADS) was used for characterizing the lesions. Results: The average age of women was 48.3 years (range; 26-81 years). There were 34 malignant and 31 benign breast lesions. The sensitivity for DM and DBT, was 73.5% and 100%, respectively, while the specificity was 67.7% and 94%, respectively. Receiver-operating characteristic curve analysis showed an overall diagnostic advantage of DBT over DM, with significant a difference between DBT and DM (p < 0.001). By performing Cohen’s kappa test, we found that there was a strong level of agreement according to Altman guidelines between DBT and histopathology findings (0.97), but there was weak agreement between DM and histopathology findings (0.47). Conclusion: DBT improves the clinical accuracy of mammography by increasing both sensitivity and specificity. We believe this improvement is due to improved image visibility and quality. These results could be of interest to health care institutions as it may impact their decision on whether to upgrade to DBT not only for diagnosis but also for screening.
关键词： Digital breast tomosynthesis,Digital mammography,Histopathology,Breast cancer
更新于2025-09-09 09:28:46
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Decrease in interpretation time for both novice and experienced readers using a concurrent computer-aided detection system for digital breast tomosynthesis
摘要： Objectives To compare the diagnostic performance and interpretation time of digital breast tomosynthesis (DBT) for both novice and experienced readers with and without using a computer-aided detection (CAD) system for concurrent read. Methods CAD system was developed for concurrent read in DBT interpretation. In this observer performance study, we used an enriched sample of 100 DBT cases including 70 with and 30 without breast cancers. Image interpretation was performed by four radiologists with different experience levels (two experienced and two novice). Each reader completed two reading sessions (at a minimum 2-month interval), once with and once without CAD. Three different rating scales were used to record each reader’s interpretation. Reader performance with and without CAD was reported and compared for each radiologist. Reading time for each case was also recorded. Results Average area under the receiver operating characteristic curve values for BI-RADS scale on using CAD were 0.778 and 0.776 without using CAD, demonstrating no statistically significant differences. Results were consistent when the probability of malignancy and percentage probability of malignancy scales were used. Reading times per case were 72.07 s and 62.03 s (SD, 37.54 s vs 34.38 s) without and with CAD, respectively. The average difference in reading time on using CAD was a statistically significant decrease of 10.04 ± 1.85 s, providing 14% decrease in time. The time-reducing effect was consistently observed in both novice and experienced readers. Conclusion DBT combined with CAD reduced interpretation time without diagnostic performance loss to novice and experienced readers.
关键词： Computer-assisted diagnosis,Digital breast tomosynthesis,Breast cancer
更新于2025-09-04 15:30:14