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Effects of lithium doping on: microstructure, morphology, nanomechanical properties and corrosion behaviour of ZnO thin films grown by spray pyrolysis technique
摘要: Li-doped ZnO thin films were prepared on glass substrate by a chemical spray pyrolysis method, in the temperature of 460 °C. The effects of Li content on the microstructural, morphological and mechanical characteristics of the doped (ZnO:Li) thin films were also examined. The XRD study showed a sharp preferred c-axis orientation and showed that (ZnO:Li) films have a würtzite structure and grow principally along the c-axis orientation with a preferred orientation (002). The film morphology was examined by (AFM) and (SEM). Results of SEM observations showed that sprayed thin films, exhibited uniform and harmonious texture. Furthermore, ZnO:Li thin films revealed uniform and spherical shaped crystallites with an approximate medium size of 200 nm. AFM characterization demonstrated an amelioration of the surface roughness of the ZnO:Li thin films. The mechanical characteristics of ZnO:Li thin films have been investigated by the nano-indentation experiment. It has been found that the addition of lithium enhances the hardness and Young’s modulus. On the other hand, the corrosion behaviour of Li-doped thin films is examined in chloride solutions. The electrochemical experiments confirmed that the lithium doping could ameliorate the anti-corrosion performance.
关键词: nanomechanical properties,morphology,microstructure,spray pyrolysis,thin films,Li-doped ZnO,corrosion behaviour
更新于2025-09-23 15:21:01
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Lipofuscin-mediated photodynamic stress induces adverse changes in nanomechanical properties of retinal pigment epithelium cells
摘要: Retinal pigment epithelium (RPE) is an important part of the blood-retina barrier (BRB) that separates the retina from the choroid. Although melanin granules contribute to the mechanical stability of the BRB complex, it is unknown if the age pigment lipofuscin affects mechanical properties of the tissue. To address this issue the effect of sub-lethal photic stress mediated by phagocytized lipofuscin granules, isolated from RPE of human donors, on morphology and mechanical properties of ARPE-19 cells was investigated. Nanomechanical analysis using atomic force spectroscopy revealed that irradiation of cells containing lipofuscin granules with blue light induced significant softening of the cells, which was accompanied by substantial reorganization of the cell cytoskeleton due to peroxidation of cellular proteins. Our results indicate that lipofuscin-mediated photic stress can cause significant modification of the RPE cells with the potential to disturb biological function of the BRB complex.
关键词: photic stress,lipofuscin,Retinal pigment epithelium,nanomechanical properties,blood-retina barrier
更新于2025-09-04 15:30:14