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- 摘要
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- 实验方案
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Therapeutic Efficacy of Home-Use Photobiomodulation Devices: A Systematic Literature Review
摘要： Objective: Perform systematic literature review on photobiomodulation (PBM) devices used at home for nonesthetic applications. Background: Home-use PBM devices have been marketed for cosmetic and therapeutic purposes. This is the first systematic literature review for nonesthetic applications. Methods: A systematic literature search was conducted for PBM devices self-applied at home at least thrice a week. Two independent reviewers screened the articles and extracted the data. Treatment dosage appropriateness was compared to the World Association for Laser Therapy (WALT) recommendations. The efficacy was evaluated according to the relevant primary end-point for the specific indication. Results: Eleven studies were suitable. Devices were applied for a range of indications, including pain, cognitive dysfunction, wound healing, diabetic macular edema, and postprocedural side effects, and were mostly based on near-infrared, pulsed light-emitting diodes with dosages within WALT recommendations. Regarding efficacy, studies reported mostly positive results. Conclusions: Home-use PBM devices appear to mediate effective, safe treatments in a variety of conditions that require frequent applications. Conclusive evaluation of their efficacy requires additional, randomized controlled studies.
关键词： low-level laser therapy,home use,over the counter,self-applied,photobiomodulation
更新于2025-09-23 15:22:29
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[ACS Symposium Series] Raman Spectroscopy in the Undergraduate Curriculum Volume 1305 || Analysis of Over-the-Counter Drugs Using Raman Spectroscopy
摘要： Commercial over-the-counter drugs such as Advil?, Aleve?, Tylenol?, Mucinex?, Excedrin?, and aspirin were analyzed with a portable handheld Raman spectrometer. The peaks from their Raman spectra were determined, and common peaks were observed in all samples. Unique peaks were also noticed and used as identifying markers to identify a particular drug. Theoretical calculations of active ingredients present in drugs were also performed, compared with experimental Raman spectra, and used to assign the functional groups responsible for the peaks. In addition, Raman spectra obtained from a benchtop instrument were also compared with that from a portable Raman spectrometer. Different forms and brands of the drugs were also analyzed to determine the effect of other materials on the active ingredient. Results showed that the dosage of active ingredients has a direct impact on the signals exhibited in Raman spectra. Lastly, different degradation processes (exposure to microwaves, UV light, and high temperature) were tested on Tylenol? and results showed peak changes in certain regions and more fluorescence background.
关键词： active ingredients,Raman spectroscopy,over-the-counter drugs,degradation processes,portable handheld Raman spectrometer
更新于2025-09-04 15:30:14