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In vitro and In vivo evaluation of green-hydrothermal synthesized ZnO nanoparticles
摘要： ZnO nanoparticles synthesized using Gallic acid isolated from Phyllanthus emblica aqueous extract that designated as Pe ZnO, was subjected for structural and morphological characterization. For in vitro cyto-toxicity assessment of Pe ZnO, Hemolytic assay and Cell Counting Kit assay (CCK 8) on balb 3T3 fibroblasts were conducted while silkworm Bombyx mori larvae were used for in vivo bio-toxicity assay. In dentistry, clinically advocated ZnO (presented as D ZnO) of ~2 μm size was used as control. Characterization results revealed that Pe ZnO is highly crystalline with hexagonal wurtzite structure and morphologically spherical with an average size of 38 nm as confirmed by X-ray diffraction, electron microscopy and dynamic light scattering techniques. Haemolysis assay at all the tested concentrations exhibit that, lysis of Red Blood Cells by Pe ZnO remained well within toxicity limit of 3% whereas D ZnO showed ~5.2% hemolysis. Interestingly, Pe ZnO nanoparticles caused less than 36% growth inhibition of 3T3 cells at the highest concentration (2 μL) against 44% by D ZnO. Notably, in vivo study showed 26.67 and 96.67% death of the larvae at highest concentration 0.032 mg/mL of Pe ZnO and D ZnO respectively indicating Pe ZnO is less toxic than commercially available ZnO. Thus, we proved that green hydrothermally synthesized ZnO (PeZnO) is highly biocompatible and therefore propose to consider as potent compound for further evaluation using mammalian models followed by clinical trials.
关键词： Hydrothermal,3T3 fibroblasts,Green synthesis,ZnO,Bombyx mori,toxicity,Hemolysis
更新于2025-09-04 15:30:14
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Indian Gooseberry-Derived Tunable Fluorescent Carbon Dots as a Promise for In Vitro/In Vivo Multicolor Bioimaging and Fluorescent Ink
摘要： We report the synthesis of eco-friendly fluorescent nitrogen-doped carbon dots (NCDs) using the renewable resource of Phyllanthus emblica juice as a precursor by the hydrothermal process at 200 °C for 12 h. The synthesized NCDs emitted bright fluorescence without any pretreatment of the sample under the excitation of UV light and exhibited excitation-dependent fluorescence emission. The NCDs have nitrogen-containing and oxygen-containing functional groups such as amino, hydroxyl, and carboxyl on the surface of the carbon structure. Furthermore, the NCDs exhibited excellent water dispersibility with prolonging stability and good biocompatibility. On the basis of the good optical properties, the NCDs have potentially been used as a promising staining agent on HCT-116 human colon cancer cells and Caenorhabditis elegans (nematodes) for multicolor cellular imaging. In the cell cytoplasm, the NCDs showed rapid uptake and high cytocompatibility on cellular morphology with bright fluorescence emission. Furthermore, the NCDs were used as fluorescent ink for writing and drawing with anticoagulation. In addition, the NCDs were significantly utilized as a fluorescent ink for thumb impression, which glows instantly under the illumination of UV light and does not require a secondary treatment. Hence, the synthesized NCDs can be used as ideal multicolor fluorescent probes for bioimaging applications and as fluorescent ink instead of traditional fluorescent ink.
关键词： nitrogen-doped,hydrothermal synthesis,carbon dots,fluorescent ink,bioimaging
更新于2025-09-04 15:30:14
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Facile <i>Justicia adhatoda</i> leaf extract derived route to silver nanoparticle: Synthesis, characterization and its application in photocatalytic and anticancer activity
摘要： The aim of the present study is to investigate the photocatalytic and anticancer activity of green synthesized silver nanoparticle (AgNPs) using leaf extract of Justicia adhatoda. Several techniques were used to confirm and characterize the synthesized AgNPs. The synthesis of nanoparticle was identified by the formation of dark brown color in the reaction mixture and SPR band noted at 425 nm. The obtained AgNPs were spherical in shape with its average sizes in the ranges of 12.0, 26.7 and 47.9 nm, respectively, it can be tuned by varying the concentration of AgNO3 analyzed by High resolution Scanning Electron Microscope and Transmission Electron Microscope (HRSEM with EDAX and TEM). The formation and size distribution of obtained AgNPs were determined by Dynamic Light Scattering (DLS) method. The negative zeta potential values were observed, causing dispersion stability of synthesized AgNPs. Fourier transform infrared spectroscopy (FTIR) and Surface Enhanced Raman (SERS) analyzed the existence of alcohols, amides and etc., in the leaf extract which behave as capping and reducing agents for the synthesis. The Face Centered Cubic (FCC) nature of AgNPs was depicted by X-Ray Diffraction analysis. The photocatalytic activity is established by size-dependent nature of AgNPs, using an organic dye (methylene blue) as a substrate. Besides, the AgNPs showed significant anticancer activity against Human lung cancer cell line (A549). From in-vitro investigation and dye degradation experimental studies confirmed that the synthesized AgNPs have potent photocatalytic as well as anticancer activity.
关键词： anticancer,photocatalytic degradation,J.adhatoda,AgNPs,Green synthesis
更新于2025-09-04 15:30:14
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Green synthesis of g-C <sub/>3</sub> N <sub/>4</sub> -Pt catalyst and application to photocatalytic hydrogen evolution from water splitting
摘要： The g-C3N4-Pt photocatalyst was successfully prepared by the combination of a biosynthesis method and sol deposition, which were used for hydrogen evolution from water splitting. The layers of g-C3N4 are thinned and the Pt nanoparticles simultaneously become tightly bound to g-C3N4 by secondary calcination in the process of synthesizing the g-C3N4-Pt photocatalyst. Analysis of the morphological structure and instrumental characterization of the optical performance revealed that the Pt nanoparticles were successfully loaded and well dispersed on the surface of g-C3N4. Furthermore, the absorption wavelength range of the g-C3N4-Pt photocatalyst in visible light was widened and the absorption increased. The activity and photostability of the g-C3N4-Pt photocatalyst for hydrogen evolution under visible light irradiation (λ≥420 nm) were excellent. The rate of H2 evolution reached 582.4 mmol h?1 g?1, and the quantum efficiency (QE) reached 2.70% at 420 nm.
关键词： green synthesis,hydrogen evolution,visible-light photocatalysis,G-C3N4-Pt photocatalyst
更新于2025-09-04 15:30:14
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[IEEE 2018 - 3DTV-Conference: The True Vision - Capture, Transmission and Display of 3D Video (3DTV-CON) - Helsinki (2018.6.3-2018.6.5)] 2018 - 3DTV-Conference: The True Vision - Capture, Transmission and Display of 3D Video (3DTV-CON) - ADAPTIVE COLOR CORRECTION IN VIRTUAL VIEW SYNTHESIS
摘要： In the paper an adaptive color correction method for virtual view synthesis is presented. It deals with the typical problem in free navigation systems – different illumination in views captured by different cameras acquiring the scene. The proposed technique adjusts the local color characteristics of objects visible in two real views. That approach allows to significantly reduce number and visibility of color artifacts in the virtual view. Proposed method was tested on 12 multiview test sequences. Obtained and presented in the paper results show, that proposed color correction provides increase of the virtual view quality measured by PSNR, SSIM and subjective evaluation.
关键词： color correction,free navigation,free-viewpoint television,virtual view synthesis
更新于2025-09-04 15:30:14
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[IEEE 2018 International Conference on 3D Vision (3DV) - Verona (2018.9.5-2018.9.8)] 2018 International Conference on 3D Vision (3DV) - Structure-Aware Shape Synthesis
摘要： We propose a new procedure to guide training of a data-driven shape generative model using a structure-aware loss function. Complex 3D shapes often can be summarized using a coarsely defined structure which is consistent and robust across variety of observations. However, existing synthesis techniques do not account for structure during training, and thus often generate implausible and structurally unrealistic shapes. During training, we enforce structural constraints in order to enforce consistency and structure across the entire manifold. We propose a novel methodology for training 3D generative models that incorporates structural information into an end-to-end training pipeline.
关键词： 3D shape synthesis,generative models,deep learning,structure-aware loss
更新于2025-09-04 15:30:14
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[IEEE 2018 IEEE International Conference on Electrical Engineering and Photonics (EExPolytech) - Saint Petersburg, Russia (2018.10.22-2018.10.23)] 2018 IEEE International Conference on Electrical Engineering and Photonics (EExPolytech) - Study of Gas-Sensitive Properties of Zinc Oxide Nanorod Array at Room Temperature
摘要： In this paper, we present a technique for the synthesis of zinc oxide nanorods and the study of their sensitivity to organic solvent vapors. Zinc oxide nanorods were synthesized by hydrothermal method. Investigation of gas-sensitive properties was carried out by the method of impedance spectroscopy. Studies of gas-sensitive properties of zinc oxide showed a significant response of the system to the vapor of reducing gases at room temperature. It is shown that the thickness of the seed layer and, correspondingly, the density of the structure on the basis of ZnO nanorods, strongly affect the sensitivity of the sensor.
关键词： impedance spectroscopy,nanorods,hydrothermal synthesis,zinc oxide,gas sensors
更新于2025-09-04 15:30:14
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Effect of Tin and Strontium Doping on the Photocatalytic Activity of Zinc Sulphide Nanoparticles for the Photocatalytic Degradation of Resorcinol under Solar and Ultra-Violet Light
摘要： Tin (Sn) and Strontium (Sr) doped Zinc Sulphide and pure Zinc Sulphide photocatalyst have been prepared by Sol-Gel method. The prepared photocatalyst have been characterised by Thermo gravimetric Differential Thermal Analysis, Scanning Electron Microscopy, Energy Dispersive X-ray, X-Ray Diffraction, ultra-violet visible spectroscopy and photoluminescence spectroscopy. Characterization Techniques have provided information of wurtzite hexagonal structure of Zinc Sulphide. The PL spectra have shown the blue shift of Zinc Sulphide after doping it with Tin and Strontium. Photocatalytic degradation study was done by the complete degradation of an organic pollutant Resorcinol in Sun light as well as in UV-light. The factors affecting the photocatalytic activity of photocatalyst viz. pH, catalyst loading and reuse of photocatalyst have been studied along with the photocatalytic degradation of Resorcinol. These external parameters have considerable influenced on the phtocatalytic activity of Zinc Sulphide.
关键词： Photocatalyst,Pollution,Sol-gel synthesis,Doping,Zinc sulphide nanoparticles,Photoluminescence
更新于2025-09-04 15:30:14
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A Cross-linked Conjugated Polymer Photosensitizer Enables Efficient Sunlight-induced Photooxidation
摘要： Photooxidation under sunlight has great potentials in organic synthesis, bacterial killing, organic waste treatment, etc. Photosensitizers (PSs) often play a very important role in this process. High 1O2 generation efficiency and excellent photostability under sunlight, as well as easy recyclability are ideal properties for PSs used for photooxidation, which are not easy to achieve simultaneously. Herein, a pure organic porous conjugated polymer PS of CPTF was designed and synthesized to show great photostability, large specific surface area and high 1O2 generation efficiency under sunlight for photooxidation in different applications. Taking the oxidation of aromatic aldehyde to aromatic acid as an example, the PS catalyst shows excellent recyclability, which enables solvent-free reactions in high yields both under direct sunlight and simulated AM1.5G irradiation. In addition, the successful application of CPTF in bacterial killing and organic waste decomposition under simulated AM1.5G irradiation indicates the potential of CPTF in sunlight-induced waste water treatment.
关键词： photooxidation,singlet oxygen,photosensitizers,sunlight-induced organic synthesis,sunlight-induced wastewater treatment
更新于2025-09-04 15:30:14
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Synthesis, Photophysical Properties and Two Photon Absorption Study of Tetraazachrysene‐based N‐heteroacenes
摘要： Three novel N-heteroacene molecules (SDNU-1, SDNU-2 and SDNU-3) based on tetraazachrysene units as cores have been designed, synthesized and fully characterized. Their photophysical, electrochemical and fluorescence properties were investigated, and they exhibited blue to green emission in solid state. Interestingly, SDNU-2 exhibited high solid photoluminescence quantum efficiencies (75.3%), which is the highest value of N-heteroacenes derivatives to date. Two-photon absorption studies have been conducted by using open and close aperture Z-scan technique. SDNU-3 showed a significant enhancement in the two-photon absorption cross-section with magnitudes as high as ～700 GM (1 GM = 1 × 10–50 cm4 s/photon) when excited with 800 nm light, which is the largest value based on heteroacene system measured by Z-scan experiment so far. We attribute the outcome to sufficient electronic coupling between the strong charge transfer of quadrupolar substituents and the tetraazachrysene core. Our result would provide a new guideline to design novel efficient two-photon materials based on N-heteroacene cores.
关键词： Synthesis,Fluorescence quantum yields,Azaacenes,Two Photon Absorption
更新于2025-09-04 15:30:14