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Choroidal Thickness at the Outside of Fovea in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography
摘要： Purpose: To evaluate choroidal thickness at the outside of the fovea in patients with diabetic retinopathy using spectral-domain optical coherence tomography. Methods: We examined 87 eyes of 87 patients with diabetic retinopathy and 40 eyes of 40 normal patients. Patients with diabetic retinopathy were divided into 3 groups according to the grade of diabetic retinopathy and macular edema. The choroidal thickness was obtained at the fovea and outside of the fovea using enhanced depth imaging of Spectralis optical coherence tomography. One foveal and 8 peripheral images were selected and choroidal thickness was measured from the outer border of the retinal pigment epithelium to the inner scleral border. Results: Subfoveal choroidal thickness was thinner with increasing severity of diabetic retinopathy. However, there was no significant difference between groups without the nasal side of the fovea. A statistically significant difference was observed over the fovea at the superotemporal area. Conclusions: The choroidal thickness outside of the fovea was thinner with the severity of diabetic retinopathy and was more pronounced in the superotemporal area.
关键词： Optical coherence tomography,Diabetic retinopathy,Choroidal thickness,Enhanced depth imaging
更新于2025-09-04 15:30:14
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A Case of Acute Bilateral Solar Retinopathy Diagnosed with Spectral Domain Optical Coherence Tomography
摘要： To report a case of acute bilateral solar retinopathy diagnosed using spectral domain optical coherence tomography (SD-OCT). Case summary: A 74-year-old female patient consulted for amblyopia and metamorphopsia at a local hospital. On the patient’s first visit, there were no abnormal findings based on slit lamp microscope. Additional examinations were conducted since the patient complained of metamorphopsia with visual acuity and corrected vision. Fundus photography and SD-OCT examination showed symmetrical lesions near the bilateral macula. Several evaluations of the patient’s medical history confirmed that the patient was exposed directly to the sun for 30 minutes. One month after the first visit, visual acuity improved but metamorphopsia remained unchanged. Lesion status could not be confirmed by fundus photography. There was no abnormal finding on fluorescence angiography. SD-OCT examination still showed bilateral symmetric disruption of the outer retina but with no significant interval change. Conclusions: In the present case, the patient with bilateral intraocular lenses who complained of acute binocular amblyopia was diagnosed accurately through SD-OCT tests for bilateral symmetric disruption on the outer retina and repetitive evaluations of patient’s medical history.
关键词： Spectral domain optical coherence tomography (SD-OCT),Acute bilateral solar retinopathy,Patient’s medical history,Disruption
更新于2025-09-04 15:30:14
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Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Diagnosis and Assessment of Takayasu Arteritis and Ulcerative Colitis
摘要： Takayasu arteritis (TA) and ulcerative colitis (UC), both immune-mediated inflammatory diseases, rarely occur together. This report describes TA in a 29-year old female patient who was being treated for UC for three years. As she had left-side neck pain and headache, she was diagnosed with TA and her response to tumor necrosis factor (TNF) inhibitor was assessed by fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT). Positive responses to the TNF inhibitor were seen by PET/CT for the TA and by endoscopy for the UC. We conclude that TNF inhibitors are effective treatments for both TA and UC. We found that PET/CT is a useful for diagnosing and assessing TA.
关键词： Positron emission tomography,Ulcerative colitis,Takayasu arteritis
更新于2025-09-04 15:30:14
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Comparison of MultiColor fundus imaging and colour fundus photography in the evaluation of epiretinal membrane
摘要： Purpose: To compare MultiColor fundus imaging (MC) and colour fundus photography (CFP) for the evaluation of epiretinal membrane (ERM). Methods: In this retrospective study, 192 eyes (181 patients) that underwent vitrectomy for ERM were imaged using Spectralis optical coherence tomography (for MC) and AFC-210 digital camera (for CFP) 1 week before vitrectomy. Two investigators independently determined the rate of delineability and ERM area for each modality. Results: The intergrader agreement rates for delineability were very high for both image modalities. The rate of delineability of ERM (%) was higher for MC than for CFP, for both investigators [70.8% versus 52.6% and 73.4% versus 53.6% (both p –)]. Epiretinal membrane (ERM) area measurement showed high agreement between investigators for MC (p = 0.466) but di?ered signi?cantly between the investigators for CFP (p –). The ERM area determined on MC was signi?cantly wider than that on CFP for both investigators (p – for investigator 1 and p – for investigator 2). Conclusion: The ERM area is more clearly detectable and widely demarcated in MC than in CFP images. MultiColor imaging (MC) may be more sensitive and accurate for early detection of ERM and ERM area measurement.
关键词： MultiColor imaging,spectral-domain optical coherent tomography,epiretinal membrane,colour fundus photography
更新于2025-09-04 15:30:14
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Retinal and Macular Ganglion Cell Count Estimated With Optical Coherence Tomography RTVUE-100 as a Candidate Biomarker for Glaucoma
摘要： To evaluate the ability of total and macular estimated retinal ganglion cell (RGC) counts to discriminate between healthy and glaucomatous eyes. To determine threshold markers of the estimated RGCs taking into account age dependence.
关键词： ganglion cells,optical coherence tomography,glaucoma
更新于2025-09-04 15:30:14
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Spectral domain optical coherence tomography imaging of subretinal bands associated with chronic retinal detachments
摘要： We report three patients with subretinal bands associated with retinal detachment in chronic retinal detachments who underwent successful retinal reattachment. Subretinal bands before and after surgery can be identified on clinical examination and spectral domain optical coherence tomography. Removal of subretinal bands is not mandatory to achieve retinal reattachment.
关键词： optical coherence tomography,retinal detachment,subretinal bands
更新于2025-09-04 15:30:14
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Detection of gallbladder stones by dual-energy spectral computed tomography imaging
摘要： AIM: To evaluate the detectability of gallbladder stones by dual-energy spectral computed tomography (CT) imaging. METHODS: Totally 217 patients with surgically confirmed gallbladder stones were retrospectively analyzed who underwent single-source dual-energy CT scanning from August 2011 to December 2013. Polychromatic images were acquired. And post-processing software was used to reconstruct monochromatic (40 keV and 140 keV) images, and calcium-lipid pair-wise base substance was selected to acquire calcium base images and lipid base images. The above 5 groups of images were evaluated by two radiologists separately with 10-year experience in CT image reading. In the 5 groups of images, the cases in the positive group and negative group were counted and then the detection rate was calculated. The inter-observer agreement on the scoring results was analyzed by Kappa test, and the scoring results were analyzed by Wilcoxon test, with P < 0.05 indicating that the difference was statistically significant. The stone detection results of the 5 groups of images were analyzed by χ2 test. RESULTS: There was good inter-observer agreement (k = 0.772). In 217 patients with gallbladder stones, there was a statistically significant difference in stone visualization between spectral images (40 keV, 140 keV, calcium base and lipid base images) and polychromatic images (P < 0.05). 40 keV monochromatic images were better than 140 keV monochromatic images (4.90 ± 0.35 vs 4.53 ± 1.15, P < 0.05), and calcium base images were superior to lipid base images (4.91 ± 0.43 vs 4.77 ± 0.63, P < 0.05), but there was no statistically significant difference between 40 keV monochromatic images and calcium base images (4.90 ± 0.35 vs 4.91 ± 0.43, P > 0.05). In 217 gallbladder stone patients, there were 21, 3, 28, 5 and 12 negative stone cases in polychromatic images, 40 keV images, 140 keV images, calcium base images and lipid base images, respectively, and the differences among the five groups were statistically significant (P < 0.05). CONCLUSION: Monochromatic images and base substance images have a good clinical prospect in the iso-density stone detection.
关键词： Gallbladder stone,Spectral imaging,Computed tomography
更新于2025-09-04 15:30:14