- 标题
- 摘要
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- 实验方案
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Synergistic Effects of Photo-Irradiation and Curcumin-Chitosan/Alginate Nanoparticles on Tumor Necrosis Factor-Alpha-Induced Psoriasis-Like Proliferation of Keratinocytes
摘要： Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation of the epidermal cells and is clinically presented as thick, bright red to pink plaques with a silvery scale. Photodynamic therapy (PDT) using visible light has become of increasing interest in the treatment of inflammatory skin diseases. In this study, we demonstrate that a combination of curcumin-loaded chitosan/alginate nanoparticles (Cur-CS/Alg NPs) and blue light emitting diodes (LED) light irradiation effectively suppressed the hyperproliferation of tumor necrosis factor-alpha (TNF-α)-induced cultured human kerlatinocyte (HaCaT) cells. The Cur-CS/Alg NPs were fabricated by emulsification of curcumin in aqueous sodium alginate solution and ionotropic gelation with calcium chloride and chitosan using an optimized formulation derived from a Box-Behnken design. The fabricated Cur-CS/Alg NPs were characterized for their particle size, zeta potential, encapsulation efficiency, and loading capacity. The surrogate 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, to measure the relative number of viable cells, showed that the CS/Alg NPs were nontoxic to normal HaCaT cells, while 0.05 μg/mL and 0.1 μg/mL of free curcumin and Cur-CS/Alg NPs inhibited the hyperproliferation of HaCaT cells induced by TNF-α. However, the Cur-CS/Alg NPs demonstrated a stronger effect than the free curcumin, especially when combined with blue light irradiation (10 J/cm2) from an LED-based illumination device. Therefore, the Cur-CS/Alg NPs with blue LED light could be potentially developed into an effective PDT system for the treatment of psoriasis.
关键词： LED light,chitosan/alginate nanoparticles,curcumin,photo-irradiation,psoriasis
更新于2025-11-19 16:56:35
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High Speed Wireless Internet Using LiFi
摘要： The internet has become a basic necessity, so with the advancement in technology, people are demanding something faster than WI-FI. Since light is the only medium that can travel fastest than any other source of data transmission else so if we use this medium for internet, it will be the best utilization of medium with a higher data transmission rate. This technology was implemented over and came out with concept of LI-FI Technology. Li-Fi in known for Light-Fidelity, Li-Fi uses an idea of visible light communication (VLC) technology that uses light as a medium to convey fast high-speed communication in a manner like Wi-Fi. Since visible light is present everywhere, the main idea of our review paper is how LI-FI technology can help in security, speed and reliability of internet and even can change our life style. This innovation is actualized utilizing white LED bulbs matched with the Downlink transmitter that can give a higher information transmission rate up to 10Gbps. The main prospective of this paper demonstrates the forthcoming routine of Li-Fi technology innovation and its highlights to expand the execution of information transmission and different applications where Li-Fi has been put to utilize.
关键词： Data utilization,Visible Light communication,Wi-Fi,server,Light-emitting diode (LED),Light-Fidelity (Li-Fi),Video LAN Client (VLC)
更新于2025-09-23 15:22:29
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Photoelectrochemical-assisted batch injection analysis (PEC-BIA) of glucose exploiting visible LED light as an excitation source
摘要： This work describes the development of a novel method for glucose determination exploiting a photoelectrochemical-assisted batch injection analysis cell designed and constructed with the aid of 3D printer technology. The PEC-BIA cell was coupled to a LED lamp in order to control the incidence of light on the Cu2O/Ni(OH)2/FTO photoelectroactive platform. The electrochemical characteristics of Cu2O/Ni(OH)2/FTO photoelectroactive platform were evaluated by cyclic voltammetry, amperometry, and electrochemical impedance spectroscopy. The PEC-BIA cell presented linear response range, limit of detection based on a signal-to-noise ratio of three, and sensitivity of 1 – 1000 μmol L-1, 0.76 μmol L-1 and 0.578 μA L μmol-1, respectively. The PEC-BIA method presented a mean value of the recovery values of 97.0 % to 102.0 % when it was applied to glucose determination in artificial blood plasma samples which indicates the promising performance of the proposed system to determine glucose.
关键词： Photoelectrochemistry,Visible LED light,Glucose,Batch injection analysis,3D-Printing,Cu2O/Ni(OH)2
更新于2025-09-23 15:21:01
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Blue LED light-driven photoelectrocatalytic removal of naproxen from water: Kinetics and primary by-products
摘要： Here, we demonstrate the viability of a ZnO/TiO2/Ag2Se thin-film composite synthesized on FTO to degrade the drug naproxen in aqueous solutions by visible-light photoelectrocatalysis (PEC). The experiments were made with 100 mL of solutions containing 5 mg L-1 drug and 50 mM Na2SO4 at natural pH, using a cell equipped with a Pt wire as cathode and the composite as photoanode exposed to a 36 W blue LED lamp. Total degradation was achieved after 210 min of electrolysis at anodic potential of +1.0 V/Ag|AgCl. This resulted from the oxidative action of hydroxyl radicals formed via direct anodic water discharge and through mediated water oxidation by photogenerated holes. The degradation rate decreased at higher naproxen concentration, but the treatment efficiency became higher due the deceleration of the parasitic reactions involving hydroxyl radicals. In chloride medium, the photoanode showed a large ability to produce active chlorine, which contributed to the oxidation of the target molecule. LC-QToF-MS analysis of treated solutions revealed the generation of four primary naphthalenic by-products, from which the initial degradation route of naproxen is proposed.
关键词： Photoelectrocatalysis,Water treatment,Oxidation by-products,Blue LED light,Pharmaceutical residue
更新于2025-09-23 15:21:01
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Defect engineered mesoporous 2D graphitic carbon nitride nanosheet photocatalyst for Rhodamine B degradation under LED light illumination
摘要： In this work, a nitrogen vacancy induced 2D mesoporous graphitic carbon nitrogen (g-C3N4) nanosheet photocatalyst was successfully synthesized through a simple two step thermal treatment method. The morphology of the nanosheet photocatalyst and the presence of nitrogen vacancy was explored through a wide range of characterization techniques. The as prepared photocatalyst possess an improved visible light absorption efficiency as confirmed from the UV-Visible diffuse reflectance spectroscopy (DRS). Moreover, the improved charge carrier separation efficiency of the nitrogen vacant material was demonstrated from the photoluminescence spectrum. Most importantly, the photocatalyst exhibited an excellent photodegradation efficiency towards rhodamine B (RhB) dye under the illumination of an 18 W LED light. The vacancy induced nanosheets demonstrated a degradation co-efficient of 0.074 min-1 in RhB degradation, which is 9.25 fold higher than that of the bulk g-C3N4. The nanosheets further exhibited an enhanced degradation efficiency toward tetracycline antibiotic. Furthermore, the photocatalyst displayed an outstanding stability even after 5 cycles. A plausible photocatalytic mechanism has also been explained based on the results obtained from the radical scavenging experiments. This study would provide insight into the defect induction mechanism into the 2D g-C3N4 nanosheet and expected to help in rationally designing vacancy induced materials with cost effective application in various environmental fields.
关键词： nitrogen vacancy,LED light irradiation,rhodamine B,mesoporous,2D g-C3N4 nanosheet
更新于2025-09-23 15:21:01
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[IEEE 2019 Photonics & Electromagnetics Research Symposium - Fall (PIERS - Fall) - Xiamen, China (2019.12.17-2019.12.20)] 2019 Photonics & Electromagnetics Research Symposium - Fall (PIERS - Fall) - A Color Compensation Method for Three Primary-color LED Light Sources
摘要： The three primary-color LED light source modules produce a color within the gamut space by the Pulse-Width-Modulation (PWM) duty cycle. In a host control multiple LED module system, due to the specificity of the three primary-color LED light sources, different light source modules cannot generate the same target color coordinates according to the same set of duty ratio data, thereby causing a color inconsistency in each light source. This paper proposes an algorithm for personalizing the Red-Green-Blue (RGB) values by using the three primary-color coordinates obtained by feedbacks. Through extensive experiments, the algorithm can effectively reduce the color difference produced by different LED lamp beads. The algorithm has a small amount of calculation and can be easily implemented in practical devices.
关键词： LED light sources,color consistency,Color compensation,RGB values,PWM
更新于2025-09-23 15:21:01
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THE EFFECTS OF CONTINUOUS LIGHTING (CL) METHOD ON THE GROWTH DEVELOPMENT OF BRASSICA CHINENSIS FOR LED PLANT FACTORY IN WSN APPLICATION
摘要： This study was performed to investigate the best practise on using LED light for optimum growth of Brassica Chinensis and reduce turn around time at different kind of photoperiod study utilizing Wireless Sensor Network (WSN) technology as remote monitoring system. Growth performance of Brassica Chinensis under two different wavelengths (blue and red) 16:4 as light source has been used to determine plant growth performance and phytochemicals aspect of plant characteristics. Two experiments were conducted which is the pulse treatment (1 hour light and 1 hour dark) and continuous light (CL) photoperiod treatment in both trials. Observation such as leaves count, height, dry weight and chlorophy I & ll of both plants were analysed. It was noted that the CL photoperiod has significant effect on overall growth performance and remarkably lead to improve the efficiency of the plant factory. In order to reason on data and monitor the environmental parameters of the plant factory, an intelligent system using embedded system has been developed to automate the LED control and manipulation. The result shows that the system is stable and has referential significantly in the area of plant factory or indoor farming system.
关键词： LED Light Spectrum,Intelligent Control Farming,Continuous Lighting,Sensor,Indoor Farming,Wireless Sensor Network,Plant Factory
更新于2025-09-23 15:21:01
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Bumblebees land remarkably well in red-blue greenhouse LED light conditions
摘要： Red-blue emitting LEDs have recently been introduced in greenhouses to optimize plant growth. However, this spectrum may negatively affect the performance of bumblebees used for pollination, because the visual system of bumblebees is more sensitive to green light than to red-blue light. We used high-speed stereoscopic videography to 3D track and compare landing manoeuvres of Bombus terrestris bumblebees in red-blue light and in regular, broad-spectrum white light. In both conditions, the landing approaches were interspersed by one or several hover phases, finally followed by leg extension and touchdown. The time between leg extension and touchdown was 25% (0.05 s) longer in red-blue light than in white light, caused by a more tortuous flight path in red-blue light. However, the total landing duration, specified as the time between the first hover phase and touchdown, did not differ between the light conditions. This suggests that the negative effects of red-blue light on the landing manoeuvre are confined to the final phase of the landing.
关键词： landing,red-blue LED light,pollination,bumblebees,greenhouse
更新于2025-09-23 15:21:01
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Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells
摘要： Exposure to blue light from light-emitting diodes (LEDs) is a source of damage for human eyes in today’s modern life. Although it is well known that blue light can cause cellular damage and death, the molecular mechanism underlying this is still not fully understood. Here, we demonstrated that exposure to blue LED light increased lysosome levels and perinuclear cluster formation in 661W murine photoreceptor-derived cells. Irradiation with blue LED light promoted the nuclear transport of transcription factor EB (TFEB) and a subsequent increase in lysosomal-related gene expression. Moreover, blue LED light induced morphological changes in lysosomal structure and lysosomal membrane permeabilization (LMP). These effects were suppressed by an antioxidant, N-acetylcysteine (NAC). Finally, a calcium ion chelator, BAPTA-AM, attenuated blue LED light-induced lysosomal biogenesis and cell death. Taken together, these findings suggest that oxidative stress under blue LED light increases lysosome levels via the TFEB pathway in a calcium-dependent manner, resulting in the accumulation of damaged lysosomes and subsequently lysosomal cell death. Our results imply that lysosomal homeostasis plays a key role in the maintenance of eye function and the progression of retinal diseases.
关键词： TFEB,Blue LED light,Calcium,Lysosome biogenesis,Oxidative stress,Lysosomal membrane permeabilization
更新于2025-09-23 15:21:01
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Rice husk derived nano-NiFe2O4@CAGC-catalyzed direct oxidation of toluene to benzyl benzoate under visible LED light
摘要： Here, we report an efficient and highly selective oxidation of primary carbon-hydrogen bond in toluene catalyzed by biomass, rice husk derived chemically activated graphitic carbon supported NiFe2O4 (nano-NiFe2O4@CAGC) nanomaterial under LED light. The hybrid nanocatalyst showed excellent activity and selectivity towards direct oxidation of toluene to benzyl benzoate. The nano-NiFe2O4@CAGC has also demonstrated superior catalytic activity compared to its individual components. The catalyst was very robust and stable under the reaction conditions, and was separated from the reaction mixture by an external magnet and reused for subsequent reactions.
关键词： reusable catalyst,nano-NiFe2O4@CAGC,oxidation of toluene to benzyl benzoate,hybrid nanocatalyst,LED light
更新于2025-09-23 15:21:01