研究目的
To evaluate the possible differences in visual quality between small incision lenticule extraction (SMILE) and femtosecond laser in situ keratomileusis (FS-LASIK) for myopia.
研究成果
SMILE and FS-LASIK are comparably safe, effective and predictable when used for the treatment of myopia. Postoperative aberration and a decrease in biomechanical effects may occur less frequently after SMILE than after FS-LASIK. Contrast sensitivity was better in the SMILE group than in the FS-LASIK group 3-6mo postoperatively.
研究不足
First, most of the studies were from Asia, which may cause publishing bias. Second, extracted data of aberration included various measurements from different wavefront analyzers, which increased the method bias.
1：Experimental Design and Method Selection:
A Meta-analysis was performed using RevMan
2：1 version software to compare the clinical outcomes of SMILE and FS-LASIK for myopia. Sample Selection and Data Sources:
Patients were from previously reported comparative studies treated with SMILE versus FS-LASIK. The PubMed, EMBASE, Cochrane, Web of Science and Chinese databases (i.e. WANFANG and CNKI) were searched in Nov. of
3：List of Experimental Equipment and Materials:
20 Not explicitly mentioned.
4：Experimental Procedures and Operational Workflow:
The differences in visual acuity, aberration and biomechanical effects within six months postoperatively were analyzed.
5：Data Analysis Methods:
The mean difference (MD) was used for continuous outcomes, and the odds ratio (OR) was calculated for dichotomous outcomes. The corresponding 95% CI was used for summary estimates, and statistically significant was a P<0.05.
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