研究目的
To explore the quantitative biological effect of laser-induced wound healing and to provide guidance for expanding the clinical application of laser therapy.
研究成果
The study concluded that with the increase in irradiation dose, skin injury appears as different types of injury plaques, ranging from mild to severe. Skin injury is worsened and the tissue repair trend is weakened with the increase in laser irradiation dose, producing a good dose-effect and time-effect relationship.
研究不足
The study was limited by the use of direct observation and histological sections to validate and evaluate laser-induced burn injury and its repair effects. Further studies using label-free imaging tools to monitor the laser damage procedure in real time and evaluate the repair progress quantitatively in vivo were suggested.
1：Experimental Design and Method Selection:
The study used a 1064 nm laser to irradiate the skin of miniature pigs at different power outputs using a grid-array method. The skin injury reaction was observed immediately after laser irradiation from low to high doses.
2：Sample Selection and Data Sources:
Six pigs with white hair were chosen, and a laser irradiation area was delimited on both sides of the spine of miniature pigs.
3：List of Experimental Equipment and Materials:
A 1064 nm laser with an output range of approximately 12 W–955 W was used. The laser power meter was used to measure the laser power through an aperture of 1 cm in diameter.
4：Experimental Procedures and Operational Workflow:
The laser irradiation spot diameter was approximately 1 cm, the irradiation time was
5：5 s, and the dose range was 4–2 J cm?The laser power was irradiated successively from small to large. Data Analysis Methods:
Matlab software was used to analyze the data results, and the damage threshold ED50 was computed.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容
