研究目的
To evaluate the feasibility and efficacy of small-incision femtosecond laser–assisted intracorneal concave lenticule implantation (SFII) and penetrating keratoplasty (PKP) in patients with progressive keratoconus.
研究成果
Both SFII and PKP surgical procedures resulted in a stable corneal volume and improved visual acuity in this long-term study. SFII was less invasive and more efficient compared with PKP.
研究不足
The change in corneal refractive power in the SFII group was not only decided by the refractive power of the graft inlayed but also dependent on anterior and posterior deformation of corneal curvature. The procedure might not improve vision in patients with an obvious corneal scar.
1：Experimental Design and Method Selection:
The study compared SFII and PKP in patients with progressive keratoconus.
2：Sample Selection and Data Sources:
31 consecutive patients (31 eyes) clinically diagnosed with progressive keratoconus were enrolled.
3：List of Experimental Equipment and Materials:
Femtosecond laser system (VisuMax; Carl Zeiss Meditec), artificial anterior chamber, Pentacam HR Scheimpflug camera, AS-OCT (DRI Triton OCT; Topcon Corporation), in vivo confocal microscopy (HRT Ⅲ; Heidelberg Engineering GmbH).
4：Experimental Procedures and Operational Workflow:
SFII involved creating a lamellar incision and implanting a concave lenticule, while PKP involved excising the host cornea and suturing a donor cornea.
5：Data Analysis Methods:
Statistical analysis was conducted using SPSS 16.0, with measurements expressed as mean ± SD.
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