研究目的
To improve the signal to noise ratio (SNR) of the fiber optic based localized surface plasmon resonance (FO?LSPR) sensor by increasing the size of gold nanoparticles (Au NPs) and reducing the background signal through surface etching.
研究成果
The proposed methods of increasing the size of Au NPs and etching the optical fiber surface effectively increased the SNR of the FO-LSPR sensor. This improvement is crucial for the accurate detection of low-concentration biomolecules, enhancing the sensor's application in disease diagnosis.
研究不足
The study does not discuss the long-term stability of the sensor or its performance under varying environmental conditions. The etching process may also introduce variability in the sensor's surface roughness.
1：Experimental Design and Method Selection:
The study involved increasing the size of Au NPs on the optical fiber surface using Au capping and etching the optical fiber surface to increase roughness, thereby reducing reflection.
2：Sample Selection and Data Sources:
Multimode optical fiber (FG105LCA, Thorlabs) was used.
3：List of Experimental Equipment and Materials:
Optical fiber cleaver (S326A, Fitel), piranha solution, sulfuric acid, hydrogen peroxide, 3-(ethoxydimethylsilyl)-propylamine, colloidal gold solution, sodium citrate dehydrate, chloride trihydrate, reactive ion etching (RIE) system.
4：Experimental Procedures and Operational Workflow:
The optical fiber was treated with piranha solution, coated with Au NPs, subjected to Au capping, and then etched using RIE.
5：Data Analysis Methods:
The LSPR signal was measured with varying refractive indices, and the SNR was calculated based on the change in sensor intensity and background noise.
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