研究目的
To investigate long-term outcomes and predictive success factors for selective laser trabeculoplasty (SLT).
研究成果
SLT is an effective method for lowering IOP in glaucoma patients over the long term. Higher pretreatment IOP was identified as a significant predictive factor for the success of SLT.
研究不足
The study is retrospective and relies on medical records, which may introduce bias. The number of patients with long-term follow-up (5 years or more) was limited to 18 eyes, which may affect the accuracy of long-term outcome analysis.
1：Experimental Design and Method Selection:
A retrospective chart review was conducted on 66 eyes of 66 glaucoma or ocular hypertension patients who underwent SLT between 2004 and
2：The IOP was measured before the treatment, at postoperative 1 week, 1 month, and every 3 months thereafter. Success was defined as an IOP decrease ≥ 3 mm Hg or ≥ 20% of the pretreatment IOP. The success rate was determined based on the Kaplan-Meier survival analysis. The predictive success factors were analyzed using the Cox proportional hazard model. Sample Selection and Data Sources:
20 Patients who underwent SLT at Yeouido St. Mary’s Hospital between 2004 and 2011 and were followed up for at least 2 years were included.
3：List of Experimental Equipment and Materials:
A 532 nm Q-switched frequency-doubled Nd:YAG laser (Coherent selecta 9000 (Selecta II), USA) was used for SLT.
4：Experimental Procedures and Operational Workflow:
SLT was performed by a single surgeon using a 532 nm Q-switched frequency-doubled Nd:YAG laser with a spot size of 400 μm, average energy of
5：6-7 mJ, and exposure time of 3 nsec. Data Analysis Methods:
The success rate was determined using Kaplan-Meier survival analysis, and predictive success factors were analyzed using the Cox proportional hazard model.
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