研究目的
To prospectively examine the effects of selective laser trabeculoplasty (SLT) on the anterior chamber angle (ACA) and its related parameters using anterior segment-optic coherence tomography (AS-OCT).
研究成果
SLT resulted in an increase in ACA, AOD and TISA when evaluated using AS-OCT. We think that this study provides a different perspective concerning the effects of SLT in the angle region and the involved mechanism.
研究不足
The most important limitation of our study is that it does not have a control group.
1:Experimental Design and Method Selection:
The study included fifty eyes of fifty patients with primary open angle glaucoma (POAG) and ocular hypertension. AS-OCT was performed before SLT application, immediately after and at 1 day and 1 month.
2:Sample Selection and Data Sources:
Eyes of volunteers aged over 18, with no previous history of intraocular surgery, SLT, iridoplasty, or iridectomy, were included following the receipts of the consent forms.
3:List of Experimental Equipment and Materials:
AS-OCT (NIDEK RS-3000, NIDEK Co. Ltd, Japan), LIGHTLas SLT Deux SLT/YAG Combination Laser (Lightmed), Carbomer Gel (Viscotears, Novartis Pharma AG, Basel, Switzerland).
4:Experimental Procedures and Operational Workflow:
One-hundred-shot SLT was applied by increasing the power by
5:1 mJ/pulse until bubbles formed in the region exposed to the laser at a 360° trabecular mesh, 400 μm spot size, 3 ns duration and an initial power of 6 mJ/pulse. Data Analysis Methods:
Statistical calculations between two dependent groups were performed using the t test. P values < 0.05 and < 0.001 were regarded as statistically significant.
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