摘要： The quality of endoscopy images has improved remarkably over the last several decades. Current generation endoscopes provide high-definition images with superior resolution and are capable of magnification as well. This means that subtle lesions are less likely to be missed on routine endoscopy. However, high definition alone may not be superior to standard white light endoscopy for in vivo characterization of polyps [1]. Differentiation of the lesions as neoplastic vs. non-neoplastic is essential as it bears implication on subsequent management and surveillance strategies. For example, hyperplastic polyps bear no malignant potential. On the other hand, adenomatous polyps harbor a definite risk of malignant transformation and need to be resected. The integration of image enhancement techniques like narrow band imaging (NBI) in the endoscopes have largely overcome the issue of discriminating neoplastic and non-neoplastic polyps in the gastrointestinal (GI) tract. Novel image enhancement techniques allow better characterization of the lesions as compared with high-definition endoscopy alone [2].