研究目的
Investigating the use of Quantum Cascade Laser (QCL) in mid-infrared and photoacoustic spectroscopy for noninvasive blood glucose detection.
研究成果
QCL-based mid-infrared and photoacoustic spectroscopy show promise for noninvasive blood glucose detection, with significant progress in sensitivity and accuracy. However, challenges remain in penetration depth, universal prediction models, and environmental sensitivity.
研究不足
The low penetration depth of mid-infrared light into human skin, the need for individual calibration models, and sensitivity to physiological and environmental changes.
1：Experimental Design and Method Selection:
The review discusses the use of QCL in mid-infrared transmission, absorption, and photoacoustic spectroscopy for blood glucose detection.
2：Sample Selection and Data Sources:
Human tissues, blood serum, and aqueous glucose solutions were used.
3：List of Experimental Equipment and Materials:
QCLs, DFB-QCLs, EC-QCLs, MCT detectors, pyroelectric detectors, and silver halide fiber optic cables.
4：Experimental Procedures and Operational Workflow:
Detailed procedures for in-vivo and in-vitro experiments, including light delivery and signal collection methods.
5：Data Analysis Methods:
Multivariate data analysis techniques, including PLSR analysis, RMSECV, RMSEP, and Clarke Error Grid Analysis.
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