研究目的
To obtain the phase-space of an electronic brachytherapy (eBT) system designed for surface skin treatments, explore the use of efficiency enhancing (EFEN) strategies in the determination of the phase-space, and perform a dosimetric characterization of the Esteya eBT system using the obtained phase-space.
研究成果
Our results agree with the published measurement results within the reported uncertainties. The observed differences in PDD, dose profiles and photon spectrum come from three main sources of uncertainty: inter-machine variations, measurements and Monte Carlo calculations. It has been observed that a mono-energetic source with a Gaussian electron distribution over the focal spot is a suitable choice to reproduce the experimental data.
研究不足
The steep absorbed dose fall-off with depth increases the volume-averaging effect of the dosimeters, affecting absorbed dose measurement accuracy. At these energies the mass energy absorption coefficients differ substantially for different body tissues, which could lead to large errors in the dose estimation whenever the dose determination is performed based on a single reference tissue.
1:Experimental Design and Method Selection:
The Monte Carlo study of the
2:5 kVp x-ray beam of the Esteya? unit was performed with PENELOPEThe EFEN strategies included the use of variance reduction techniques and mixed Class II simulations, where transport parameters were fine-tuned. Sample Selection and Data Sources:
Four source models were studied varying the most relevant parameters characterizing the electron beam impinging the target: the energy spectrum (mono-energetic or Gaussian shaped), and the electron distribution over the focal spot (uniform or Gaussian shaped).
3:List of Experimental Equipment and Materials:
The Esteya? unit (Elekta Brachytherapy, Veenendaal, The Netherlands) with a set of conical applicators of 10 mm, 15 mm, 20 mm, 25 mm and 30 mm diameter.
4:Experimental Procedures and Operational Workflow:
Phase-spaces obtained were analyzed to detect differences in the calculated data due to the EFEN strategy or the source configuration. Depth dose curves and absorbed dose profiles were obtained for each source model and compared to experimental data previously published.
5:Data Analysis Methods:
The MC efficiency ε is defined as the inverse of the variance of the evaluated specific score multiplied by the CPU time required to simulate the number of particles N.
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