研究目的
Investigating the therapeutic effects of surface-enhanced Raman scattering (SERS) on biomedical applications, including bioanalysis in vitro and in vivo, and its potential to surpass traditional analytical, labelling, and healthcare diagnostic technologies.
研究成果
SERS has a huge potential of opening the landscape of current diagnostic strategies. By adequate design of nanomaterials, SERS can be a very sensitive tool for ultratrace analysis of bioactive molecules so far undetectable. The high specificity of SERS further contributes to detect very low concentration of bioanalytes, going beyond the state of the art in the early diagnosis of diseases like cancer, Alzheimer’s or Parkinson’s disease.
研究不足
The main limitation in SERS stems from the plasmonic substrate itself, leading to inconsistent signal intensities and reproducibility issues. The complexity of biological samples and the lack of specific chemical groups with affinity to the plasmonic surface also pose challenges.
