研究目的
To determine the effectiveness of the method for preventing corneal opacity and minimizing the intraocular pressure (IOP) increase after photorefractive keratectomy treated with 0.1% fluorometholone and tranilast (0.5% tranilast, Krix?, JW pharmaceutical, Seoul, Korea), especially in cases with elevated IOP.
研究成果
Adding tranilast eye drops to patients whose IOP was elevated because of 0.1% fluorometholone use after photorefractive keratectomy is an effective method for preventing corneal haze and minimizing IOP elevation.
研究不足
The study is limited by its retrospective design and the subjective assessment of corneal haze using slit-lamp microscopy.
1:Experimental Design and Method Selection:
The study compared patients who underwent photorefractive keratectomy and were treated with
2:1% fluorometholone and tranilast eye drops (tranilast group) with a control group that used only 1% fluorometholone. Sample Selection and Data Sources:
Patients who underwent photorefractive keratectomy from May 2014 to May 2015 (tranilast group) and from December 2012 to October 2013 (control group) were enrolled.
3:List of Experimental Equipment and Materials:
Allegretto Wave Eye-Q Laser; Alcon, Fort Worth, TX, USA was used for the surgery.
4:Experimental Procedures and Operational Workflow:
Postoperative management included the use of
5:1% fluorometholone and tranilast eye drops in the tranilast group and only 1% fluorometholone in the control group. Data Analysis Methods:
Statistical analysis was performed using SPSS 15.0 program.
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