研究目的
To investigate the hemodynamics of the choriocapillaris in primate eyes under elevated intraocular pressure.
研究成果
The choriocapillaris lobules appear to be supplied from peripheral arterioles, not central. After blood perfuses the lobules, it drains into the venules at the center. Mosaic or lobular patterns during FA may reflect extravasated fluorescein from the fenestrated choriocapillaris.
研究不足
Only two animals were studied, hence the experiments should be repeated in other primates.
1:Experimental Design and Method Selection:
The study used indocyanine green angiography (ICGA) and fluorescein angiography (FA) to observe the hemodynamics of the choriocapillaris in primate eyes under elevated intraocular pressure.
2:Sample Selection and Data Sources:
Two healthy monkeys (Macaca fuscata) were used in the study.
3:List of Experimental Equipment and Materials:
Heidelberg retinal angiography (HRA; Heidelberg, Inc., Heidelberg, Germany) was used for angiography.
4:Experimental Procedures and Operational Workflow:
Angiography was performed in the left eye of each animal after elevation of the intraocular pressure to 35 and 60 mm Hg.
5:Data Analysis Methods:
The angiograms for the FA and ICGA were superimposed using a photo editing program (Photoshop version 13; Adobe Systems, Inc.).
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