研究目的
To develop a rapid, colorimetric, and easy visual determination method for cyanide ions (CNˉ ions) in water using gold nanoparticles stabilized with β-cyclodextrin (β-CD).
研究成果
The β-CD AuNPs based colorimetric assay is a simple, rapid, and highly sensitive method for the detection of CNˉ ions in water, with a detection limit below the WHO permissible limit. The method shows excellent specificity and has been successfully applied to real water samples. The development of a cotton swab based test stripe offers a portable and convenient tool for on-site detection of CNˉ ions.
研究不足
The study does not address the potential interference from complex matrices or the long-term stability of the β-CD AuNPs in environmental samples.
1:Experimental Design and Method Selection:
The study utilized β-cyclodextrin stabilized gold nanoparticles (β-CD AuNPs) for the colorimetric detection of CNˉ ions. The method is based on the etching of β-CD AuNPs surface by CNˉ ions, leading to a change in the SPR band and colorimetric nature of the nanoparticles.
2:Sample Selection and Data Sources:
Real water samples (tap and drinking water) were used to validate the method.
3:List of Experimental Equipment and Materials:
Equipment included a UV?visible spectrophotometer, FT-IR spectrophotometer, HR-TEM, and DLS. Materials included HAuCl4, β-CD, NaOH, and NaCN.
4:Experimental Procedures and Operational Workflow:
β-CD AuNPs were synthesized and characterized. The detection of CNˉ ions was performed by observing changes in the SPR band and colorimetric response.
5:Data Analysis Methods:
The sensitivity and specificity of the method were evaluated through absorption titration experiments and selectivity tests against various anions.
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