研究目的
Investigating the enhancement of sensitivity in SPR optical biosensors based on Graphene-MoS2 structure with a nanocomposite layer.
研究成果
The proposed SPR optical biosensor based on Graphene-MoS2 structure with a nanocomposite layer achieves a maximum sensitivity of ～200°/RIU with six layers of MoS2 and a nanocomposite layer containing gold nanoparticles and TiO2 as host dielectric. The study demonstrates the potential of using hybrid nanostructures for enhancing the sensitivity of SPR biosensors.
研究不足
The study is based on numerical simulations and theoretical modeling, which may not fully capture all practical aspects of biosensor fabrication and operation. The optimal parameters identified may vary in real-world applications due to manufacturing tolerances and environmental conditions.
1：Experimental Design and Method Selection:
The study involves designing a hetero-structured Air/MoS2/Nanocomposite/MoS2/Graphene optical biosensor using Otto configuration for SPR. The methodology includes theoretical modeling and numerical analysis to investigate the sensitivity enhancement.
2：Sample Selection and Data Sources:
The study uses numerical simulations to analyze the effect of various parameters on the biosensor's sensitivity, including the refractive index of the prism, thickness of the nanocomposite layer, and the number of MoS2 layers.
3：List of Experimental Equipment and Materials:
The materials considered include BK7, SF10, and 2S2G prisms, MoS2 layers, graphene, and nanocomposite layers with gold nanoparticles and TiO2 as host dielectric.
4：Experimental Procedures and Operational Workflow:
The study involves calculating the reflected intensity of p-polarized incident light using the matrix method for N-layer model, investigating the influence of various parameters on sensitivity, and determining optimal values for maximum sensitivity.
5：Data Analysis Methods:
The sensitivity, detection accuracy, and quality factor of the biosensor are calculated based on the SPR curve and the shift in the SPR angle of incidence.
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