研究目的
To evaluate visual function related to tear stability in patients with dry eye (DE) using a functional visual acuity (FVA) measurement system and to assess its efficacy in detecting minimal visual deterioration and determining the efficacy of treatments for DE disease.
研究成果
The FVA measurement system is a simple, noninvasive, and sensitive method to assess visual function in DE. It is useful to detect minimal visual deterioration, assess and quantify vision-related symptomatology, and determine the efficacy of treatments for DE disease. Its use has expanded to analyze visual function in various ocular conditions, and it may be expected to be used worldwide.
研究不足
The FVA measurement system is currently only available in Japan, limiting its global use. Additionally, the system's effectiveness may depend on the patient's ability to respond accurately within the set time.
1:Experimental Design and Method Selection:
The FVA measurement system was developed to assess visual function in DE by measuring the change in visual acuity (VA) over time automatically. The system evaluates visual function related to tear stability in patients with DE.
2:Sample Selection and Data Sources:
Patients with aqueous-deficient DE and short tear breakup tear film DE characterized by decreased tear stability and minimal epithelial damage were selected.
3:List of Experimental Equipment and Materials:
The FVA measurement system, including the instrument body, a monitor displaying an optotype, and a joystick for responses, was used.
4:Experimental Procedures and Operational Workflow:
The FVA testing was performed under full refractive correction and spontaneous blinking without topical anesthesia. The test begins with the best-corrected Landolt VA, which is the baseline VA. Patients delineate the orientation of the automatically presented Landolt ring on the built-in screen in the peeping-type equipment by handling the joystick from the baseline VA from the start.
5:Data Analysis Methods:
The results are recorded as a list of timewise VA with decimal notations and logMAR conversion. The continuous VA change is plotted in a graph.
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