1：Experimental Design and Method Selection:

The nanogels were synthesized via one-pot thiol-ene Michael addition polymerization of resveratrol triacrylate, 1,6-hexanedithiol, and methoxyl poly(ethylene glycol) acrylate under the catalysis of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).

2：0]undec-7-ene (DBU). Sample Selection and Data Sources:

2. Sample Selection and Data Sources: Trans-resveratrol was used as the starting material, and the nanogels were characterized using various techniques including NMR, FT-IR, TEM, SEM, DLS, UV-vis spectroscopy, and fluorescence spectroscopy.

3：List of Experimental Equipment and Materials:

Materials included trans-resveratrol, methoxyl poly(ethylene glycol), DBU, HDT, acryloyl chloride, and other reagents and solvents. Equipment included a Bruker NMR spectrometer, Bio-Rad Win-IR instrument, JEOL JEM-1011 transmission electron microscope, Wyatt QELS instrument, Zeiss Merlin field emission scanning electron microscope, Shimadzu UV-2401 PC spectrometer, and PTI quanta master fluorescence spectrometer.

4：Experimental Procedures and Operational Workflow:

The synthesis involved the preparation of resveratrol triacrylate, followed by copolymerization with mPEGA and HDT. The product was purified by dialysis and lyophilization. Characterization included size determination, stability tests, and fluorescence measurements.

5：Data Analysis Methods:

Data were analyzed using standard curve methods for UV-vis spectroscopy, Image J software for TEM images, and relative intensity calculations for fluorescence measurements.