研究目的
To implement and evaluate the diagnostic ability of a new iNAV approach for dual-phase 3D WH bSSFP in healthy volunteers and patients with congenital heart disease, using separate systolic and diastolic image navigators with CRUISE gating.
研究成果
The proposed iNAV motion compensation technique for dual phase 3D WH bSSFP significantly reduces scan time compared to the conventional approach in both healthy subjects and patients with congenital heart disease without significantly compromising image quality. This shortened acquisition time will improve clinical applicability and patient comfort.
研究不足
The study did not compare the relative contribution of correction or gating when comparing iNAV to dNAV due to technical limitations. Additionally, the iNAV approach failed to yield diagnostic image quality in a few cases, and the dNAV approach had to be aborted in two patients due to extremely low gating efficiency.
1：Experimental Design and Method Selection:
The study implemented a dual-phase 3D WH bSSFP with iNAV motion compensation technique, comparing it to the conventional dNAV approach. Separate systolic and diastolic iNAV references were used for motion correction and CRUISE gating.
2：Sample Selection and Data Sources:
Nineteen healthy volunteers and thirty patients with congenital heart disease were included. All experiments were performed on a
3：5 T clinical scanner. List of Experimental Equipment and Materials:
A
4：5 T clinical scanner (Ingenia, Philips Healthcare, Best, The Netherlands) using a 32-channel cardiac coil. Experimental Procedures and Operational Workflow:
Dual-phase 3D WH bSSFP scans were acquired with both dNAV and iNAV motion compensation in a randomized order. Acquisition time was recorded, and image quality was assessed.
5：Data Analysis Methods:
Vessel sharpness and length were measured for the RCA, LAD, and LCx arteries in both cardiac phases. Qualitative and quantitative analyses were performed in a blinded and randomized fashion.
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