研究目的
The objective of this work is the evaluation of the final effective dose (E), considering the dose from a CT scan and according to the activity of the radiopharmaceutical [18F]FDG injected into the patient.
研究成果
CT scans contribute 78.2% of the effective dose in PET/CT examinations, emphasizing the need for protocol optimization to reduce patient exposure. Individualized radiopharmaceutical dosing based on body mass can lower doses. Training for professionals is crucial for effective radiological protection.
研究不足
The study used a phantom, which may not fully replicate human variability. Doses were evaluated in specific organs, and results are dependent on the protocols and equipment used. Optimization of protocols and individualized calculations are needed for broader applicability.
1：Experimental Design and Method Selection:
The study evaluated absorbed and effective doses from CT scans and radiopharmaceutical incorporation in 19 organs using an Alderson Rando phantom and radiochromic films. Methods included CT scanning protocols and dose calculations based on ICRP models.
2：Sample Selection and Data Sources:
An Alderson Rando male phantom with tissue-equivalent material was used, sliced into 33 sections with points for dose evaluation. Data were collected from film strips placed in organs.
3：List of Experimental Equipment and Materials:
Equipment includes a Discovery 690 PET/CT system (General Electric), Alderson Rando phantom, Gafchromic XR-QA2 radiochromic film, and ImageJ software. Materials include the phantom and film strips.
4：Experimental Procedures and Operational Workflow:
The phantom was positioned in the PET/CT scanner; frontal and lateral scout scans were performed. CT protocols included whole-body and high-resolution lung scans. Film strips were scanned post-CT, and doses were calculated using calibration curves and software analysis.
5：Data Analysis Methods:
Absorbed doses were calculated from film darkness using a calibration curve. Effective doses were computed using ICRP publication 106 models, incorporating tissue weighting factors and radiation types. Statistical analysis included mean values and uncertainties.
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