研究目的
To report the results using Micropulse? transscleral cyclophotocoagulation (Iridex) in the treatment of glaucoma.
研究成果
In a heterogeneous glaucoma population, a single session of Micropulse? transscleral cyclophotocoagulation resulted in a low success rate (27.3%) at medium-term follow-up, with no complications reported. Longer treatment durations (180 seconds) showed better outcomes, but statistical significance could not be established. Prospective studies with larger sample sizes and longer follow-up are needed to evaluate long-term efficacy and safety.
研究不足
Retrospective design, small sample size (22 eyes), heterogeneous patient population with difficult-to-manage glaucoma types, inability to determine statistical significance for treatment duration trends due to sample size, and short to medium-term follow-up (mean 7.9 months).
1:Experimental Design and Method Selection:
Retrospective observational study using Micropulse? transscleral cyclophotocoagulation with fixed laser parameters (2 W power, 0.5 ms active cycle) and variable treatment duration (100-180 seconds). The same surgical technique was applied to all patients.
2:5 ms active cycle) and variable treatment duration (100-180 seconds). The same surgical technique was applied to all patients.
Sample Selection and Data Sources:
2. Sample Selection and Data Sources: Adult patients with glaucoma, at least 6 months of follow-up, only one session of Micropulse?. Patients had various types and stages of glaucoma, mainly congenital and pseudoexfoliation.
3:List of Experimental Equipment and Materials:
Micropulse? infrared diode laser (Iridex), peribulbar block with lidocaine 2%, lubricating gel or artificial tears.
4:Experimental Procedures and Operational Workflow:
Patients received local anesthesia or mild sedation. Laser treatment applied over 360 degrees, avoiding 3 and 9 o'clock positions. Probe moved slowly and uniformly in clockwise-counterclockwise manner. Treatment duration varied by surgeon (100s, 160s, or 180s).
5:Data Analysis Methods:
Statistical analysis using IBM SPSS Statistics 23.0. Preoperative and postoperative IOP compared with Wilcoxon signed-rank test. Success defined as IOP between 5-21 mmHg, ≥20% reduction from baseline, no addition of oral carbonic anhydrase inhibitors, and no re-operation.
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