研究目的
To evaluate the suitability of the PTW 60019 microDiamond detector for small field dosimetry in cyberknife photon beams.
研究成果
The PTW 60019 microDiamond detector demonstrates excellent dose linearity, minimal dose rate dependence, and high spatial resolution, making it a suitable candidate for small field dosimetry. It shows close agreement with diode detectors but with better tissue equivalence, reducing overestimation issues in output factors. Future studies should include Monte Carlo simulations for enhanced validation.
研究不足
The study is limited to CyberKnife photon beams and specific detector models; results may vary with other systems. The small field sizes pose challenges in detector positioning and volume effects. Monte Carlo simulations or further validations are suggested for broader applicability.
1:Experimental Design and Method Selection:
The study involved measuring dose linearity, dose rate dependence, output factors (OF), percentage depth doses (PDD), and off center ratio (OCR) for small photon beams using a CyberKnife system and comparing results with other detectors (PinPoint ionization chamber, diamond detector, microLion liquid ionization chamber, diode detector).
2:Sample Selection and Data Sources:
Measurements were performed on 6 different collimator sizes (5 mm to 30 mm) in a CyberKnife system, with data collected using a water phantom.
3:List of Experimental Equipment and Materials:
Equipment included PTW 60019 microDiamond detector, PTW 31014 PinPoint chamber, PTW 60003 diamond detector, PTW 31018 microLion, PTW 60008 diode detector, PTW MP3-XS water phantom, PTW UNIDOSE electrometer, and a linear accelerator (Clinac iX, Varian) for some measurements.
4:Experimental Procedures and Operational Workflow:
Dose linearity was measured at 100 cm SSD, 10x10 cm2 field, 5 cm depth with varying MU. Dose rate dependence was measured similarly with varying MU/min. OF was measured at 80 cm SAD, 1.5 cm depth for collimator sizes 5-60 mm. PDD was scanned from water surface to 25 cm depth at 80 cm SSD. OCR was measured at 80 cm SAD, 5 cm depth with lateral scans. All measurements were repeated three times for reliability.
5:5 cm depth for collimator sizes 5-60 mm. PDD was scanned from water surface to 25 cm depth at 80 cm SSD. OCR was measured at 80 cm SAD, 5 cm depth with lateral scans. All measurements were repeated three times for reliability. Data Analysis Methods:
5. Data Analysis Methods: Data were normalized and compared using linear fit functions for dose linearity, and differences were calculated in percentages for dose rate dependence, OF, PDD ratios, and penumbra sizes.
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microDiamond detector
PTW 60019
PTW
Used for measuring dose linearity, dose rate dependence, output factors, percentage depth doses, and off center ratio in small field photon beam dosimetry.
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PinPoint chamber
PTW 31014
PTW
Used as a comparison detector for output factors and other dosimetric parameters.
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Diamond detector
PTW 60003
PTW
Used as a comparison detector for dosimetric measurements.
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microLion
PTW 31018
PTW
Used as a comparison detector, specifically a liquid ionization chamber for dose rate dependence measurements.
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Diode detector
PTW 60008
PTW
Used as a comparison detector, known for its small size and use in small field dosimetry.
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Water phantom
PTW MP3-XS
PTW
Used for holding water to simulate human tissue during dosimetry measurements.
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Electrometer
PTW UNIDOSE
PTW
Used to measure charge during dosimetry experiments.
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Linear accelerator
Clinac iX
Varian
Used for dose linearity and dose rate dependence measurements with a 6 MV photon beam.
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CyberKnife system
Kuka
The primary radiation therapy system used for small field dosimetry with various collimator sizes.
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