研究目的
To develop software for image processing in support of THz imaging for early detection of gastric cancer, enhancing accuracy and selectivity of images.
研究成果
TDS-THz can identify affected tissues or cancerous areas at early stages based on lower absorption of tumors at certain THz frequencies. The developed software enhances image accuracy and selectivity, emphasizing volume differences and interfaces between normal and cancerous tissues, providing precise information for surgery procedures. Future work should focus on versatility across frequencies and measurement modes.
研究不足
THz imaging modalities are characterized by poor signal-to-noise ratio, slow processing, low brightness, and specific procedures for clinical exposure. The software must be versatile and adaptable to different measurement variants under TDS-THz methodology.
1:Experimental Design and Method Selection:
The methodology involves using Terahertz time-domain spectroscopy (TDS-THz) for imaging, combined with software development for image processing techniques such as contrast enhancement, histogram equalization, unsharp masking, Laplacian sharpening, statistical differencing, image segmentation, and volume visualization.
2:Sample Selection and Data Sources:
Biological samples, including reference materials and suspected tumoral tissues, are used. Data is acquired through scanning with TDS-THz systems.
3:List of Experimental Equipment and Materials:
TDS-THz system (specific model not mentioned), software for image processing, reference biological samples.
4:Experimental Procedures and Operational Workflow:
Calibration with reference materials, scanning of samples to generate time-domain signals, conversion to frequency domain using Fast Fourier Transform (FFT), application of apodisation techniques to remove noise, data analysis including contrast enhancement and other image processing routines, and visualization of 2D and 3D images.
5:Data Analysis Methods:
Statistical techniques for image enhancement, FFT for signal processing, and software routines for synchronizing colormaps and emphasizing differences in tissue absorption.
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