研究目的
To discuss the early screening of hypertension using the morphological features of photoplethysmography (PPG) and establish a risk stratification approach.
研究成果
The study established a PPG characteristic analysis model and intrinsic relationship between SBP and PPG features, achieving high F1 scores for hypertension risk stratification (up to 92.31% for normotension vs. hypertension). Features related to the b to d wave interval were most informative, reflecting physiological changes in cardiovascular circulation. Future work should focus on long-term dynamic monitoring and improving algorithms for real-world applications.
研究不足
The study examined correlation only with systolic blood pressure (SBP), not diastolic or mean arterial pressure; classification between prehypertension and hypertension was not investigated; high sampling rate (1 kHz) may lead to power consumption issues in wearable devices; data were collected in a controlled environment, not real-world conditions.
1:Experimental Design and Method Selection:
The study involved designing a portable hardware platform for PPG signal acquisition, defining and extracting 125 morphological features from PPG and its derivatives, using six feature selection methods (Spearman correlation, ReliefF, information gain, chi-square, mRMR, Gini index) to evaluate features, and establishing linear and nonlinear classification models (LDA, cubic SVM, weighted KNN, logistic regression) for hypertension risk stratification.
2:Sample Selection and Data Sources:
Data were collected from 219 subjects recruited from Guilin People's Hospital, with exclusions for certain diseases and medications, resulting in a final dataset of 124 subjects categorized into normotensive, prehypertensive, and hypertensive groups based on BP criteria.
3:List of Experimental Equipment and Materials:
A customized PPG probe with an MSP430FG4618 MCU, infrared transmission mode at 905-nm wavelength, 1 kHz sampling rate, 12-bit ADC,
4:5–12 Hz bandpass filter, and an Omron 7201 electronic sphygmomanometer for BP measurement. Experimental Procedures and Operational Workflow:
Participants rested for over 30 minutes, then PPG signals were collected from the left index finger and BP from the right forearm simultaneously within 3 minutes using the custom probe and Omron device; three
5:1-s PPG records per subject were saved, and physiological data were recorded via a mobile app. Data Analysis Methods:
Data pre-processing included signal quality evaluation using skewness method, bandpass filtering, mathematical derivatives for VPG and APG, feature extraction, z-score normalization, feature selection, and classification with 10-fold cross-validation using MATLAB R2017a.
独家科研数据包,助您复现前沿成果,加速创新突破
获取完整内容