研究目的
To provide an overview of current fluorescence-guided neurosurgery techniques, including the use of fluorescent contrast agents and excitation light sources, and to discuss future directions such as handheld devices, dual fluorophore imaging, metabolic imaging, and tumor margin detection.
研究成果
Fluorescence-guided neurosurgery enhances intraoperative visualization of brain tumors and vascular structures using agents like 5-ALA, fluorescein, and ICG. Future advancements in handheld technologies, dual fluorophore imaging, metabolic imaging integration, and tumor margin detection hold promise for improving surgical outcomes and precision in neurosurgery.
研究不足
The chapter is a review and does not present new experimental data; limitations include reliance on existing literature, potential biases in cited studies, and the need for further clinical validation of emerging technologies like handheld devices and dual fluorophore imaging.
1：Experimental Design and Method Selection:
The paper is a review chapter, not an experimental study, so it does not describe specific experimental designs or methods. It summarizes existing knowledge and technologies in fluorescence-guided neurosurgery.
2：Sample Selection and Data Sources:
Based on literature review and clinical studies, including fluorescent agents like 5-ALA, fluorescein, and ICG, and their applications in neurosurgery.
3：List of Experimental Equipment and Materials:
Operative microscopes with filter sets, excitation light sources (e.g., blue light for 5-ALA), NIR cameras, and handheld spectroscopic devices are mentioned but not detailed with specific models.
4：Experimental Procedures and Operational Workflow:
Describes general procedures for using fluorescent agents intraoperatively, such as administration methods and visualization techniques, but no step-by-step protocols.
5：Data Analysis Methods:
Not applicable as it is a review; references to studies involving sensitivity and specificity measurements are cited.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容
