研究目的
To critique the approach by Hruska et al. for quantifying tissue differences using molecular breast imaging and background parenchymal uptake, highlighting its limitations and advocating for true tissue quantification methods.
研究成果
The authors conclude that the approach by Hruska et al. is flawed due to incorrect modeling and lack of true quantification, emphasizing the need for standardized, calibrated methods to accurately differentiate tissue types and measure treatment responses.
研究不足
The paper discusses limitations of existing methods, including lack of standardization and calibration of nuclear cameras, use of non-absolute ratios, and inability to measure transitional changes in tissue, but does not specify its own experimental limitations.