研究目的
To evaluate the secondary and exploratory outcomes of the LEAD study, focusing on the effect of SNL treatment on the progression to late AMD in its early stages.
研究成果
Subthreshold nanosecond laser treatment did not delay progression to late AMD significantly in the non-treated, fellow eyes of individuals with bilateral large drusen. There was generally no significant effect of SNL treatment on the rate of change for drusen volume, visual function, and participant-reported outcomes.
研究不足
The study did not find a significant effect of SNL treatment on the rate of progression to late AMD in the non-treated, fellow eyes. The mechanism of action of the SNL treatment on progression to late AMD may be independent from those captured by the exploratory outcome measures.
