研究目的
Investigating the efficacy of a novel ultraviolet light-emitting diode device for decontamination of shared pens in a health care setting to reduce the transmission of health care?associated pathogens and respiratory viruses.
研究成果
A novel UV-C device was effective in reducing contamination with non-spore-forming bacteria and an enveloped virus on pens. We recommend that additional studies be performed in health care settings to evaluate the efficacy of the device in reducing transmission of pathogens by shared writing utensils.
研究不足
The study has some limitations. We tested only one UV-C cycle, whereas in clinical settings pens could receive numerous cycles per day. We did not test the efficacy of the device for decontamination of styluses. We did not compare the efficacy of the device with wiping with a disinfectant wipe. In practice, however, wiping of pens is uncommon. Finally, we did not include an assessment of the impact of factors such as relative humidity, temperature, or dust on the LED surface on the efficacy of decontamination.
1：Experimental Design and Method Selection:
The study tested the effectiveness of a novel device for pen decontamination that uses ultraviolet-C (UV-C) light produced by light-emitting diodes (LEDs). The Steri-Write system was used for semiautomated pen decontamination and dispensing.
2：Sample Selection and Data Sources:
The study tested the efficacy of the device against 1 strain each of MRSA, carbapenem-resistant Escherichia coli, C dif?cile spores, VRE, Candida auris, the non-enveloped bacteriophage MS2, and the enveloped bacteriophage Phi X
3：List of Experimental Equipment and Materials:
1 The Steri-Write system (Steri-Write; North Canton, OH) is a small portable device designed for semiautomated pen decontamination and dispensing. The device contains 4 LEDs that emit 265-nm UV-C.
4：Experimental Procedures and Operational Workflow:
Pens placed in the top of the device are automatically loaded onto a conveyer system that rotates the pens to provide UV-C exposure to all sides for a total exposure time of 30 or 90 seconds. After cycle completion, decontaminated pens are dispensed at the base of the device.
5：Data Analysis Methods:
Log10 CFU or PFU reductions were calculated by comparing recovery from writing utensils after decontamination versus untreated controls. For each organism, triplicate samples were tested, and reductions for the 30- and 90-second exposures were compared by Student t-test.
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