研究目的
To study the long-term safety and efficacy of contact TCP in eyes with refractory glaucoma after penetrating keratoplasty (PKP).
研究成果
Cyclodiode laser treatment with initial selective 180-degree protocol seems to be an efficient therapeutic option in the management of patients with refractory glaucoma post-PKP when compared with other surgical alternatives. A selective 180-degree protocol seems to potentially reduce the rate of complications.
研究不足
The study is retrospective and lacks randomization. The sample size is relatively small, and the follow-up period, although long, may not capture all potential long-term complications.
1：Experimental Design and Method Selection:
Retrospective observational single-center cohort study.
2：Sample Selection and Data Sources:
All consecutive patients treated with TCP for refractory glaucoma following PKP between March 1996 and February 2017 in a tertiary corneal transplantation service in the United Kingdom.
3：List of Experimental Equipment and Materials:
G-Probe (Iridex Corporation, Mountain View, CA) disposable contact transscleral diode probe.
4：Experimental Procedures and Operational Workflow:
TCP technique of administration was similar for all patients with a standardized fractioned and selective 180-degree protocol.
5：Data Analysis Methods:
Statistical analysis was performed using Xlstat, version 2017.3 (Addinsoft) software.
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