摘要： Previous studies have shown that liquid crystal display (LCD) can cause visual fatigue to the human eye, but the effect of quantum dot (QD) display has not been explored yet. This study conducted a human factor experiment on the QD display and LCD. The parameters ACC, HOAs and MTF were selected as objective physiological indicators for visual quantification of visual fatigue. 39 participants performed a 45-minute video viewing task. While before and after the visual task, measured the physiological parameters of the participants' eyes. Analysis the effects of QD display and LCD on human physiological characteristics under the same conditions. The results show that: (1) The QD display and LCD have an influence on the physiological characteristics of the human eye during continuous visual task duration. These effects can be quantified by changes in human eye physiological parameters; (2) The effect of QD display on human eye physiological parameters is less than LCD: the VICO index (visual comfort index) is lower, and the participants' color feedback accuracy is higher. This study provides theoretical basis and data support for the subsequent development of quantum dot display.