摘要： Laser cutting is one of the most widely used thermal energy based non-contact type advance machining process. In recent years, considerable experimental investigations have been carried out aiming at improving laser cutting process performance. In this work CO2 laser cutting parameters on stainless steel 304 width 2.5 mm thickness were studied. The cut quality achieved minimum kerf width to cut stainless steel sheet depends on appropriate selection process parameters was investigated. The parameters consider to include laser output power, cutting speed, gas pressure. The effect of cutting parameter on the cut quality was further investigated by monitoring top kerf width, and bottom kerf width using box –behnken designing the response surface methodology. And finally optimized best CO2 laser cutting parameters are selected by using genetic algorithm approach.