研究目的
Investigating the thermal effects and damage caused by laser irradiation on biological tissues using a two-temperature heat conduction model.
研究成果
The study demonstrated significant impacts of various parameters (positions, two-temperature parameter, laser pulse dimensions, penetration depth, time, and power density) on conductive and dynamical temperature increments and thermal damage. Increasing certain parameters (two-temperature parameter, penetration depth, time, and power density) increased temperature increments and damage, while increasing others (position and laser pulse dimensions) decreased them. The findings contribute to understanding thermal damage in biological tissues subjected to laser irradiation.
研究不足
The study relies on mathematical modeling and simulations, which may not fully capture the complexity of biological tissues and laser-tissue interactions in real-world scenarios. The model's accuracy depends on the assumptions and parameters used.
1：Experimental Design and Method Selection:
The study constructed and applied bioheat transfer equations within a two-temperature heat conduction model to analyze temperature variations in laser-irradiated biological tissue. The Laplace and Fourier transform techniques were used to solve the equations.
2：Sample Selection and Data Sources:
A homogeneous skin tissue sample in three dimensions was considered, subjected to a rectangular laser pulse.
3：List of Experimental Equipment and Materials:
The study utilized mathematical models and simulations rather than physical equipment.
4：Experimental Procedures and Operational Workflow:
The governing equations were applied to the three-dimensional biological tissue, with the surface subjected to a rectangular laser pulse. Thermal damage was calculated using the Arrhenius integral.
5：Data Analysis Methods:
The inverse of the double Fourier and Laplace transforms was found to solve the problem in the physical domain, using the Riemann sum approximation method for Laplace transform inversion.
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