研究目的
To present a general strategy for the preparation of a fully organic X-ray radioluminescent colloidal platform that can be tailored to emit anywhere in the visible spectrum through a judicious choice in donor/acceptor pairing and multiple sequential F?rster resonance energy transfers (FRETs).
研究成果
A fully organic X-ray radioluminescent colloidal platform was developed, capable of emitting across the visible spectrum through sequential FRETs. The emission can be dynamically tuned by assembling the particles into crystalline colloidal arrays, offering potential applications in X-ray luminescence-based medical imaging with reduced toxicity concerns.
研究不足
The study focuses on the preparation and characterization of organic X-ray radioluminescent colloidal platforms. Potential toxicity effects in vivo and the efficiency of energy transfer in different environments are areas for further investigation.
1：Experimental Design and Method Selection
A modified emulsion polymerization procedure was followed to synthesize polystyrene particles doped with various dyes. The particles were assembled into crystalline colloidal arrays to demonstrate emission tuning through a coupling of rejection wavelength with the dyes’ emission.
2：Sample Selection and Data Sources
Three different types of ≈100 nm particles doped with anthracene as the scintillating molecule and subsequent FRET dye pairs were used. Optical and X-ray characterization was performed using various spectrometers and imaging techniques.
3：List of Experimental Equipment and Materials
Amptek Mini-X X-ray unit, Canon EOS Rebel T6 camera, fiber optic bundle connected to a grating spectrometer, bifurcated fiber optic bundle connected to a spectrometer, Perkin-Elmer Lambda 950 UV/VIS/NIR spectrophotometer.
4：Experimental Procedures and Operational Workflow
Particles were synthesized, purified, and characterized. Optical and X-ray imaging and spectroscopy were performed to analyze the emission characteristics and the effect of crystalline colloidal arrays on emission tuning.
5：Data Analysis Methods
Emission spectra were analyzed to determine the effect of FRET and crystalline colloidal arrays on emission characteristics. Color characteristics were quantified using the 1931 International Commission on Illumination (CIE) chromaticity diagram.
独家科研数据包，助您复现前沿成果，加速创新突破
获取完整内容-
Canon EOS Rebel T6 camera
EOS Rebel T6
Canon
Used for capturing optical images of the samples under X-ray illumination.
暂无现货
预约到货通知
-
spectrometer
USB2000
Ocean Optics
Used for analyzing the reflection spectra of the samples.
立即获取同款设备
-
white light source
LS-1-CAL
Ocean Optics
Used for illuminating the samples to obtain reflection spectra.
暂无现货
预约到货通知
-
UV/VIS/NIR spectrophotometer
Lambda 950
Perkin-Elmer
Used for obtaining absorbance spectra of the samples.
暂无现货
预约到货通知
-
Amptek Mini-X X-ray unit
Amptek
Used for X-ray excitation of the samples.
暂无现货
预约到货通知
-
fiber optic bundle
Oriel
Connected to a grating spectrometer for obtaining X-ray radioluminescence spectra.
暂无现货
预约到货通知
-
grating spectrometer
MicroHR
Jobin Yvon
Used for analyzing the emission spectra of the samples.
暂无现货
预约到货通知
-
bifurcated fiber optic bundle
Ocean Optics
Connected to a spectrometer for obtaining reflection spectra.
暂无现货
预约到货通知
-
登录查看剩余6件设备及参数对照表
查看全部
