研究目的
To examine the effectiveness of terahertz (THz) pulsed imaging (TPI) in comparison to intraoral photostimulable phosphor late (PSP) and cone beam CT (CBCT) for the detection of dental caries ex vivo.
研究成果
Terahertz pulsed imaging was found to be successful for the detection of dental caries ex vivo, showing excellent intra- and interobserver agreements and comparable performance to PSP and CBCT images.
研究不足
The study was conducted ex vivo, which may not fully replicate clinical conditions. The presence of water in real clinical situations could affect THz imaging results. The sample size was limited to 32 teeth surfaces.
1：Experimental Design and Method Selection:
The study utilized a TPI system in reflection mode to investigate tooth samples in three dimensions. The methodology included comparing THz imaging with PSP and CBCT images for caries detection.
2：Sample Selection and Data Sources:
Newly extracted 32 human permanent teeth surfaces (16 with caries and 16 without caries) were serially sectioned mesiodistally and imaged.
3：List of Experimental Equipment and Materials:
The TPI system included an ultrafast mode-locked Erbium (Er) doped fiber laser, CBCT unit (ProMax? 3D Max CBCT), and PSP digital intraoral system (Digora Optime DXR-50).
4：0). Experimental Procedures and Operational Workflow:
4. Experimental Procedures and Operational Workflow: Teeth were imaged using CBCT, PSP, THz movie video, and THz static images. Images were evaluated by two observers for caries presence/absence.
5：Data Analysis Methods:
Weighted κ coefficients were calculated for intra- and interobserver agreement. Receiver operating characteristic analysis was used to compare image sets with the histological gold-standard.
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