研究目的
To evaluate the changes in each retinal layer thickness according to preoperative optical coherence tomography (OCT) patterns after idiopathic epiretinal membrane (ERM) removal and to investigate the correlation between retinal layer thickness and visual improvement.
研究成果
In patients with idiopathic ERM, preoperative difference in each retinal layer thickness according to preoperative OCT patterns was observed. After ERM removal, reduction of each retinal layer thickness and specific retinal layer related to visual improvement was different according to preoperative OCT patterns.
研究不足
The study was limited by its retrospective design and the relatively small sample size. Additionally, the exclusion of patients with certain conditions may limit the generalizability of the findings.
1：Experimental Design and Method Selection:
The medical records of 63 patients (63 eyes) who underwent vitrectomy with internal limiting membrane (ILM) peeling for idiopathic ERM and followed for more than 6 months were retrospectively reviewed. The OCT images of preoperative idiopathic ERM were classified into 3 patterns being flat, convex, and concave. Then, the changes of each retinal layer thickness were compared among OCT patterns and the correlations between retinal layer thickness and visual improvement were analyzed.
2：Sample Selection and Data Sources:
The OCT images were obtained using CirrusTM HD-OCT 4000 (Carl Zeiss Meditec, Dublin, CA).
3：List of Experimental Equipment and Materials:
CirrusTM HD-OCT 4000 (Carl Zeiss Meditec, Dublin, CA).
4：Experimental Procedures and Operational Workflow:
The OCT images of preoperative idiopathic ERM were classified into 3 patterns being flat, convex, and concave. Then, the changes of each retinal layer thickness were compared among OCT patterns and the correlations between retinal layer thickness and visual improvement were analyzed.
5：Data Analysis Methods:
The statistical analysis was performed using SPSS 12.0 program (Standard version 12.0, SPSS INC., Chicago, IL).
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