- 标题
- 摘要
- 关键词
- 实验方案
- 产品
-
Nanomechanical Microfluidic Mixing and Rapid Labelling of Silica Nanoparticles with Allenamide to Thiol Covalent Link for Bioimaging
摘要: Rapid surface functionalization of nanomaterials using covalent linkage following ‘green chemistry’ remains challenging and the quest for developing simple protocols are persisting. We report a nanomechanical microfluidic approach for the coupling of allenamide functionalized organic derivatives on the surface of thiol modified silica nanoparticles using allenamide-thiol chemistry. The coupling principle involves the use of a microfluidic surface acoustic wave (SAW) device that generates acoustic streaming based chaotic fluid micromixing that enables mixing of laterally flowing fluids containing active components. This approach was used to demonstrate the direct surface labeling of thiol modified silica nanoparticles using a selected group of modified fluorescence tags containing allenamide handles and achieved a total efficiency of 83-90 %. This green approach enabled a highly efficient surface functionalization in aqueous conditions, with tunable control over the conjugation process via the applied field. The dye labelled silica particles were characterized using various analytical techniques and found to be biocompatible with a potential in live cell bioimaging. It is envisaged that this bioconjugation strategy will find numerous applications in the field of bioimaging and drug delivery.
关键词: microfluidics,surface acoustic wave (SAW),allenamide-thiol chemistry,bioimaging,nanoparticles
更新于2025-09-23 15:23:52
-
Magnetostrictive effect in micro-dotted FeCo film coated surface acoustic wave devices
摘要: The magnetostrictive effect in micro-dotted FeCo film coated surface acoustic wave (SAW) devices was demonstrated by solving coupling equations using the specific coupling of modes parameters extracted by FEM analysis. Dotted-pattern on FeCo thin-film proposed in this work contributes well to suppression in hysteresis effect by fully releasing the internal coericivity of the magnetistrictive FeCo thin-film. The theoretical demonstration was confirmed well by characterizing the constructed SAW magnetic devices with FeCo dots depositing along the SAW propagation path. Significantly improvements on suppression of hysteresis phenomenon were observed by characterizing the prepared FeCo dots coated SAW magnetic devices, higher magneto-sensitivity of 21.17 kHz mT?1, and lower hysteresis error of 0.82% were achieved successfully.
关键词: magnetostrictive effect,coupling of modes,hysteresis,micro-dotted FeCo film,SAW magnetic device
更新于2025-09-23 15:23:52
-
[IEEE 2018 IEEE International Ultrasonics Symposium (IUS) - Kobe, Japan (2018.10.22-2018.10.25)] 2018 IEEE International Ultrasonics Symposium (IUS) - SH-Type Spurious Response Free TC-SAW Resonators Using Low Acoustic Velocity Rayleigh SAW on LiNbO<inf>3</inf> Substrate
摘要: In this paper, we describe the behavior of the spurios resonance caused by shear-horizontal (SH) type surface acoustic wave (SAW) devices in low acoustic velocity (LAV) Rayleigh-type SAW structures. It is well known that an SH-type SAW or Rayleigh-type SAW device appears near the main resonance on LiNbO3 (LN) substrates, which causes various undesired effects on the device characteristics. However, they are often non-negligible in practical use. In order to explore a solution of this problem, we theoretically and experimentally investigated the variation of the SH-type SAW resonance in the low acoustic velocity (LAV) Rayleigh-type SAW structure on LN substrates, which is a new LAV-SAW structure with a higher performance temperature-compensated (TC) SAW device (TC-SAW) technology. As a result, we revealed that the SH-type SAW can be almost zero even if various parameters are changed. Moreover, very small sized and TC-SAW devices can be realized using this new technology.
关键词: temperature compensation,SAW,Rayleigh-type SAW,acoustic velocity,LiNbO3,SH-type SAW
更新于2025-09-23 15:22:29
-
[IEEE 2018 IEEE International Ultrasonics Symposium (IUS) - Kobe, Japan (2018.10.22-2018.10.25)] 2018 IEEE International Ultrasonics Symposium (IUS) - Hierarchical Cascading in FEM Simulations of SAW Devices
摘要: Application of the finite element method (FEM) for the simulation of SAW devices has traditionally been constrained by the large number of degrees-of-freedom required, resulting in large memory usage and long computation times, and limiting the accuracy of the simulation. In this paper we review the recently introduced hierarchical cascading method, which offers drastically reduced memory consumption and simulation times in 2D simulations. In 3D, the advantages of hierarchical cascading are diminished due to the high number of cross-sectional degrees-of-freedom. As a partial solution to this problem, an iterative hierarchical cascading method is proposed, with reduced number of effective degrees-of-freedom. Examples of simulations of finite devices in 2D and of a periodic array in 3D are provided.
关键词: FEM,SAW simulation,SAW
更新于2025-09-23 15:22:29
-
[IEEE 2018 Wave Electronics and its Application in Information and Telecommunication Systems (WECONF) - Saint-Petersburg, Russia (2018.11.26-2018.11.30)] 2018 Wave Electronics and its Application in Information and Telecommunication Systems (WECONF) - MEMS Accelerometer with SAW
摘要: was created the model of a microaccelerometer using MEMS technology. Were investigated the sensitivity and non-linear properties of the MEMS sensor in the commercial temperature range.
关键词: microaccelerometer with SAW,slaser stimulated plasma etching,MEMS technology
更新于2025-09-23 15:22:29
-
[IEEE 2018 IEEE International Ultrasonics Symposium (IUS) - Kobe, Japan (2018.10.22-2018.10.25)] 2018 IEEE International Ultrasonics Symposium (IUS) - Low-Loss, High-Frequency and Large-Coupling SH SAW Resonators Based on SiN/LiNbO<inf>3</inf>/Si
摘要: Low-loss, high-frequency and large-coupling-coefficient SAW resonators based on SiN/LN/Si are demonstrated in this study. By bonding the high-velocity Si substrate to the sub-wavelength-thick LN layer, the shear-horizontal mode SAW resonator no longer couples with the bulk modes in substrate and the leaky component is effectively eliminated. As the propagation loss is no longer the main concern for the cut angle selection, the ultra-large cut angle can be used to achieve high coupling coefficient (κ2). By carefully designing the SiN/LN/Si structure, the high-frequency and large-κ2 SAW resonators with low loss are achieved. The fabricated SAW resonators show great potential for current and next generation front ends.
关键词: SiN/LN/Si,large coupling coefficient,high frequency,low loss,SAW resonators
更新于2025-09-23 15:22:29
-
[ACM Press the 2017 2nd International Conference - Wuhan, China (2017.11.07-2017.11.09)] Proceedings of the 2017 2nd International Conference on Communication and Information Systems - ICCIS 2017 - Effect of Concentration on Surface Acoustic Wave Velocity in A Rayleigh-type Biosensor
摘要: To predict the propagation velocity of different concentrations of bovine serum albumin (BSA) in a Rayleigh-type biosensor, we derived a new calculation method for a Rayleigh surface acoustic wave (SAW) device. The method can calculate propagation velocities of leaky Rayleigh waves and Rayleigh waves when liquid is placed in the groove of a Rayleigh-type SAW device. Different concentration of BSA proteins were used to evaluate the effect of these concentrations. In this study, we used different concentrations of BSA and a Rayleigh-type SAW device consisted of grooves of 0.25 mm width and 0.26 mm height and grooves of 0.40 mm width and 0.25 mm height, quartz as the substrate and interdigital transducers (IDT) with a 25.00 mm distance. The frequency of the Rayleigh-type SAW device was set to 157.6 MHz. Our data suggests that the propagation velocity of SAWs depends mainly upon BSA protein concentration and the size of groove. At the same concentration of BSA, the propagation acoustic wave velocity of BSA depends on the size of groove. The results showed the 0.40 mm width-0.25 mm height groove was more suitable than the 0.25 mm width-0.26 mm height groove for studying the propagation velocity of wave with liquid in a Rayleigh-type SAW device. With the propagation velocity decreased when the concentration of BSA protein increased.
关键词: Surface acoustic wave (SAW),Rayleigh-type SAW device,Leaky Rayleigh wave,Bovine serum albumin (BSA),Rayleigh wave
更新于2025-09-23 15:21:01
-
Highly selective and label-free Love-mode surface acoustic wave biosensor for carcinoembryonic antigen detection using a self-assembled monolayer bioreceptor
摘要: A love-mode surface acoustic wave (SAW) biosensor based on ST-cut quartz was developed for highly selective and label-free detection of carcinoembryonic antigen (CEA). The delay line area of an interdigital transducer (IDT) based SAW device was coated with gold and then chemically modified through thioglycolic acid–EDC/NHS reaction mechanism. A self-assembled monolayer of anti-CEA was further immobilized on the bioreceptors through the coupling layer. The biosensing capability of the SAW device was evaluated using solutions of CEA with various concentrations and limit of detection was obtained at 0.31 ng/ml of CEA, which is better than the results reported by the literatures available for CEA detection using SAW device. The real-time detection capability of the biosensor was evaluated using clinical serum samples and selectivity was evaluated using mixed solutions of CEA with other common tumor marking proteins. Long-term stability of the biosensor was also evaluated over a period of 30 days and the immunoassay response has shown only 8% decrease in performance within the whole period. The binding of CEA onto the bioreceptor was evaluated through Langmuir and Freundlich sorption isotherm kinetic studies as well.
关键词: SAW,Piezoelectricity,Biosensing,CEA,Label free,SAM
更新于2025-09-23 15:19:57
-
Development of additive-assisted Ag-MACE for multicrystalline black Si solar cells
摘要: The uniform distribution of silver nanoparticles on the surfaces of diamond-wire sawn multicrystalline silicon (mc-Si) is critical for the texturing of mc-Si by the Ag metal-assisted chemical etching method (Ag-MACE). In this study, an additive containing alkylphenol polyoxyethylene is developed to improve the Ag-MACE process. It enables an even deposition of the silver nanoparticles over the surface of the silicon wafer, so that the entire wafer surface can be uniformly textured with nanostructures. The experimental results show that the additive improves the appearance and performance of solar cells, including their reflectivity, efficiency, internal quantum efficiency and external quantum efficiency. Mass-produced mc-Si solar cells textured using Ag-MACE with this additive have achieved a maximum efficiency of 19.51%, compared with an efficiency of 19.16% for cells fabricated without the additive.
关键词: metal-assisted chemical etching,additive,diamond wire saw,uniform textures,solar cell,multicrystalline silicon
更新于2025-09-23 15:19:57
-
Investigation into effect of coupled resonance phenomenon towards sensitivity enhancement of SAW conductivity sensors integrated with ZnO nanorods
摘要: In this work, FEM simulation was used to investigate the sensitivity of a one-port surface acoustic wave (SAW) resonator sensor to changes in electrical conductivity of the sensing medium composed of ZnO nanorods offering elastic loading on the surface of the resonator. A system of coupled resonators was formed when the height of the ZnO nanorods attached to the surface of the resonator was adjusted such that the resonant frequency of the nanorod approached the original resonant frequency of the SAW resonator. It was observed that the use of ZnO nanorods of resonant dimensions as sensing medium could enhance the sensitivity of the composite SAW sensor to changes in electrical conductivity of the sensing medium by up to 79 times. The comparatively higher sensitivity of the SAW conductivity sensor utilizing ZnO nanorods at resonant dimensions as sensing medium was attributed to the fact that the system of coupled resonators thus formed operates at a state of high sensitivity to changes induced in piezoelectric stiffening of the substrate during SAW propagation. The observations from FEM simulation conducted in the present work suggests strong prospects for the use of coupled resonance phenomenon at nanoscale for enhancing the sensitivity of conductivity-based SAW gas sensors and UV detectors employing 1-D ZnO nanostructures as sensing medium.
关键词: ZnO nanorods,sensitivity enhancement,SAW resonator,coupled resonance,FEM simulation
更新于2025-09-23 15:19:57