研究目的
To prepare silicon naphthalocyanine nanoparticles by laser ablation in liquid for use as contrast agents in photoacoustic imaging and to investigate their optical properties.
研究成果
Silicon naphthalocyanine nanoparticles were successfully prepared by laser ablation in liquid. The particle sizes were decreased with an increase in laser fluence, and the absorption peak wavelength was about 800 nm, suitable for photoacoustic imaging. The change in the ratio of the two peaks at the Q band suggests a crystal structure change.
研究不足
The study does not address the long-term stability of the nanoparticles in biological environments or their toxicity, which are crucial for biomedical applications.
1：Experimental Design and Method Selection:
Silicon 2,3-naphthalocyanine bis(trihexylsilyloxide) raw-material powder was ultrasonically dispersed in deionized water and irradiated with Nd:YAG laser to prepare nanoparticles.
2：Sample Selection and Data Sources:
The raw-material powder was used as the sample.
3：List of Experimental Equipment and Materials:
Nd:YAG laser, scanning electron microscope (SEM), dynamic light scattering (DLS) device, spectrophotometer.
4：Experimental Procedures and Operational Workflow:
The solution was stirred and irradiated with laser for 30 min. The particles obtained were characterized by SEM, DLS, and spectrophotometry.
5：Data Analysis Methods:
The morphology and particle size were investigated by SEM and DLS. The absorption spectra were measured by spectrophotometry.
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