研究目的
Investigating the integration of photoacoustic imaging on clinical ultrasound imaging platforms without hardware synchronization or access to pre-beamformed channel RF data.
研究成果
The study presented an economic PA imaging platform that allows broader PA imaging research community to use refurbished or retired US scanner without hardware synchronization or access to pre-beamformed channel RF data. The method showed good accuracy and robustness in LTF estimation and comparable spatial resolution to conventional PA imaging.
研究不足
1. Limited scenarios regarding the rate difference between laser excitation and US data acquisition were presented. 2. The requirement for post-beamformed RF data, which is not accessible from all current clinical platforms. 3. The algorithm runs off-line, reducing its efficacy in practical investigation. 4. The method requires programmable laser system, not an option provided by every laser system.
1：Experimental Design and Method Selection:
The study involves the development of line trigger frequency (LTF) estimation and asynchronous synthetic aperture inverse beamforming (ASAIB) for PA imaging on clinical US platforms.
2：Sample Selection and Data Sources:
Simulation data was generated using k-Wave toolbox in MATLAB, and phantom experiments were conducted using an externally triggered Ultrasonix Sonix CEP system.
3：List of Experimental Equipment and Materials:
A 1-D linear array probe with 128-elements, a single PZT element for mimicking a PA point target, and function generators for controlling frequencies.
4：Experimental Procedures and Operational Workflow:
The method involves tuning the pulse repetition into different frequencies, estimating the deadtime, and applying ASAIB for image reconstruction.
5：Data Analysis Methods:
The performance was validated through simulation and phantom study, focusing on the accuracy of LTF estimation and the quality of reconstructed images.
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