研究目的
The aim of this study was to evaluate the impact of corneal cross-linking combined with photorefractive keratectomy (PRK) on blurring strength.
研究成果
Only the combined treatment (tCxL) resulted in significant reduction in blurring strength. The excellent correlation of blurring strength with NEI-VFQ scores indicates its reliability as an index of self-reported quality of life in keratoconus.
研究不足
The study was a nonrandomized trial, which may introduce selection bias. The sample size, although adequate for the study's power, may limit the generalizability of the findings. The follow-up period was limited to 12 months, which may not capture long-term effects.
1：Experimental Design and Method Selection:
A prospective, observational, nonrandomized trial was conducted. The impact of surgical procedure on blurring strength was assessed by power vector analysis.
2：Sample Selection and Data Sources:
63 patients with keratoconus were recruited, forming two study groups according to the therapeutic intervention.
3：List of Experimental Equipment and Materials:
UV-XTM (IROC AG, Zürich, Switzerland) for UVA light irradiation, Allegretto Wave 200 Hz (WaveLight Laser Technologie, AG, Erlangen, Germany) for photorefractive ablation.
4：Experimental Procedures and Operational Workflow:
Patients underwent either CxL or combined CxL with tCxL treatments. Follow-up visits were performed postoperatively.
5：Data Analysis Methods:
Power vector analysis was used to evaluate the impact on refraction. Statistical analysis was performed using MedCalc statistical program.
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